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3,876 Newest Publications of Expert Reviews

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Intelligent use and clinical benefits of electronic health records in rheumatoid arthritis

08-Feb-2015 | Robert J Carroll; Anne E Eyler; Joshua C Denny, Expert Review of Molecular Diagnostics, 2015

In the past 10 years, electronic health records (EHRs) have had growing impact in clinical care. EHRs efficiently capture and reuse clinical information, which can directly benefit patient care by guiding treatments and providing effective reminders for best practices. The increased adoption has ...

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Dose modification of anti-TNF in rheumatoid arthritis and estimated economical impact: a review of observational studies

02-Jan-2015 | Joaquín Borrás-Blasco; Andres Navarro Ruiz, Expert Review of Pharmacoeconomics & Outcomes Research, 2015

Anti-TNF drugs indicated for the treatment of moderate-to-severe active rheumatoid arthritis (RA) presents similar efficacy, safety and potential toxicity profiles, with more than 10 years’ treatment experience. Several pharmacoeconomic evaluations had demonstrated their favorable ...

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Further understanding of tau phosphorylation: implications for therapy

02-Jan-2015 | Miguel Medina; Jesús Avila, Expert Review of Neurotherapeutics, 2015

Tau is a brain microtubule-associated protein that regulates microtubule structure and function. Prominent tau neurofibrillary pathology is a common feature in a number of neurodegenerative disorders collectively referred to as tauopathies, the most common of which is Alzheimer’s disease. Beyond ...

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Utility estimates for patients with Type 2 diabetes mellitus after experiencing a myocardial infarction or stroke: a systematic review

02-Jan-2015 | Victoria K Brennan; Josephine Mauskopf; Ann D Colosia; Catherine Copley-Merriman; Bastian Hass; Roberto Palencia, Expert Review of Pharmacoeconomics & Outcomes Research, 2015

A systematic review identified studies eliciting utility decrements from myocardial infarction (MI) and stroke in patients with Type 2 diabetes mellitus (T2DM) and examined their use in economic models of new diabetes treatments. In 16 utility studies in patients with T2DM, utility decrements in ...

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Targeting the neurophysiology of cognitive systems with transcranial alternating current stimulation

30-Dec-2014 | Flavio Fröhlich; Kristin K Sellers; Asa L Cordle, Expert Review of Neurotherapeutics, 2014

Cognitive impairment represents one of the most debilitating and most difficult symptom to treat of many psychiatric illnesses. Human neurophysiology studies have suggested that specific pathologies of cortical network activity correlate with cognitive impairment. However, we lack demonstration ...

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Incorporating sign-dependence in health-related social welfare functions

29-Dec-2014 | Arthur E Attema, Expert Review of Pharmacoeconomics & Outcomes Research, 2014

It is important to measure people’s preferences regarding the trade-off between efficiency and equity in health to make public decisions that are in a society’s best interests. This article demonstrates the usefulness of social welfare functions to obtain these measurements. Insights from ...

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Belimumab for the treatment of systemic lupus erythematosus

29-Dec-2014 | Natasha Jordan; David P D’Cruz, Expert Review of Molecular Diagnostics, 2014

Given their pivotal role in autoantibody production, B-cells have become an attractive therapeutic target in systemic lupus erythematosus (SLE). Belimumab, a fully human monoclonal antibody against B lymphocyte stimulator (BLyS), a B-cell survival factor, was licensed in 2011 for the treatment of ...

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Progress in measuring family spillover effects for economic evaluations

29-Dec-2014 | J Mick Tilford; Nalin Payakachat, Expert Review of Pharmacoeconomics & Outcomes Research, 2014

Despite considerable progress in measuring family spillover effects for economic evaluations, much work remains. This editorial describes recent advances in the field and identifies areas for future research. In particular, we point out the need to clarify the potential for double-counting from ...

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Evaluation of the eZono 4000 with eZGuide for ultrasound-guided procedures

29-Dec-2014 | Jeff Gadsden; Malikah Latmore; Daniel M Levine, Expert Review of Medical Devices, 2014

Ultrasound-guided procedures are increasingly common in a variety of acute care settings, such as the operating room, critical care unit and emergency room. However, accurate judgment of needle tip position using traditional ultrasound technology is frequently difficult, and serious injury can ...

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Charting a path toward combination therapy for Alzheimer’s disease

26-Dec-2014 | Diane Stephenson; Dan Perry; Cynthia Bens; Lisa J Bain; Donald Berry; Michael Krams; Reisa Sperling; David Dilts; Jo ..., Expert Review of Neurotherapeutics, 2014

It is acknowledged that progress in combined therapeutic approaches for Alzheimer’s disease (AD) will require an unprecedented level of collaboration. At a meeting co-hosted by the Accelerate Cure/Treatments for Alzheimer’s Disease Coalition and the Critical Path Institute, investigators from ...

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