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467 Newest Publications in nature clinical practice rheumatology
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IL-27 links lipids to autoimmunity
25-May-2018 | Nicholas J. Bernard, Nature Clinical Practice Rheumatology, 2018
IL-27 links lipids to autoimmunity IL-27 links lipids to autoimmunity, Published online: 25 May 2018; doi:10.1038/s41584-018-0026-4 IL-27 links lipids to autoimmunity
AhR controls tolerance to cell debris
23-May-2018 | Joanna Collison, Nature Clinical Practice Rheumatology, 2018
AhR controls tolerance to cell debris AhR controls tolerance to cell debris, Published online: 23 May 2018; doi:10.1038/s41584-018-0024-6 AhR controls tolerance to cell debris
Existing and novel biomarkers for precision medicine in systemic sclerosis
22-May-2018 | Peter J. Wermuth; Sonsoles Piera-Velazquez; Joel Rosenbloom; Sergio A. Jimenez, Nature Clinical Practice Rheumatology, 2018
The discovery and validation of biomarkers resulting from technological advances in the analysis of genomic, transcriptomic, lipidomic and metabolomic pathways involved in the pathogenesis of complex human diseases have led to the development of personalized and rationally designed approaches for ...
Neurobiological similarities between RA and fibromyalgia
15-May-2018 | Fabiola Atzeni; Piercarlo Sarzi-Puttini, Nature Clinical Practice Rheumatology, 2018
Neurobiological similarities between RA and fibromyalgia Neurobiological similarities between RA and fibromyalgia, Published online: 15 May 2018; doi:10.1038/s41584-018-0011-y Pain management can be a difficult problem for patients with rheumatoid arthritis (RA), some of whom can experience pain ...
Fyn-ding a target for OA therapy
14-May-2018 | Nicholas J. Bernard, Nature Clinical Practice Rheumatology, 2018
Fyn-ding a target for OA therapy Fyn-ding a target for OA therapy, Published online: 14 May 2018; doi:10.1038/s41584-018-0020-x Fyn-ding a target for OA therapy
Biomarkers as drug development tools: discovery, validation, qualification and use
14-May-2018 | Virginia B. Kraus, Nature Clinical Practice Rheumatology, 2018
The 21st Century Cures Act, approved in the USA in December 2016, has encouraged the establishment of the national Precision Medicine Initiative and the augmentation of efforts to address disease prevention, diagnosis and treatment on the basis of a molecular understanding of disease. The Act ...
Multimerized IgG1 Fc molecule as an anti-inflammatory agent
14-May-2018 | Emmanuel Stephen-Victor; Jagadeesh Bayry, Nature Clinical Practice Rheumatology, 2018
Multimerized IgG1 Fc molecule as an anti-inflammatory agent Multimerized IgG1 Fc molecule as an anti-inflammatory agent, Published online: 14 May 2018; doi:10.1038/s41584-018-0013-9 The success of intravenous immunoglobulin immunotherapy in autoimmune diseases has inspired the development of ...
The role of radiography and MRI for eligibility assessment in DMOAD trials of knee OA
11-May-2018 | Frank W. Roemer; C. Kent Kwoh; Daichi Hayashi; David T. Felson; Ali Guermazi, Nature Clinical Practice Rheumatology, 2018
Currently, no disease-modifying osteoarthritis drugs (DMOADs) have been approved. Past clinical trials have failed for several reasons, including the commonly applied definition of eligibility based on radiographic assessment of joint structure. In the context of precision medicine, finding the ...
Denosumab shows promise for GIOP
11-May-2018 | Sarah Onuora, Nature Clinical Practice Rheumatology, 2018
Denosumab shows promise for GIOP Denosumab shows promise for GIOP, Published online: 11 May 2018; doi:10.1038/s41584-018-0016-6 Denosumab shows promise for GIOP
Axial disease in psoriatic arthritis and ankylosing spondylitis: a critical comparison
11-May-2018 | Joy Feld; Vinod Chandran; Nigil Haroon; Robert Inman; Dafna Gladman, Nature Clinical Practice Rheumatology, 2018
Ankylosing spondylitis (AS) was first identified in the late 17th century. 250 years later, inflammatory spine disease was recognized to be one of the patterns of psoriatic arthritis (PsA). Isolated spondylitis is rare among patients with PsA, occurring in less than 5% of patients; however, many ...
