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697 Newest Publications in international journal of obesity


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The anorexigenic peptide neurotensin relates to insulin sensitivity in obese patients after BPD or RYGB metabolic surgery

24-May-2018 | Christian Loeffelholz; Lidia Castagneto Gissey; Tina Schumann; Christine Henke; Anica Kurzbach; Joachim Struck; Andr ..., International Journal of Obesity, 2018

Neurotensin is a peptide with effects on appetite and intestinal lipid absorption. Experimental data suggest a role in glucose homeostasis, while human data is missing. Here, 20 morbidly obese subjects either underwent biliopancreatic diversion with duodenal switch (BPD), or Roux-en-Y gastric ...


Kinetics of human brown adipose tissue activation and deactivation

24-May-2018 | Brooks P. Leitner; Lauren S. Weiner; Matthew Desir; Peter A. Kahn; Daryl J. Selen; Cathy Tsang; Gerald M. Kolodny; A ..., International Journal of Obesity, 2018

Brown adipose tissue (BAT) has been identified as a potential target in the treatment and prevention of obesity and metabolic disease. The precise kinetics of BAT activation and the duration of stimulus required to recruit metabolically active BAT, and its subsequent deactivation, are not ...


Maternal obesity aggravates the abnormality of porcine placenta by increasing N6-methyladenosine

24-May-2018 | Tongxing Song; Jinxin Lu; Zhao Deng; Tao Xu; Yue Yang; Hongkui Wei; Shengqing Li; Siwen Jiang; Jian Peng, International Journal of Obesity, 2018

The growing prevalence of overweight or obese pregnancies shows an increasing risk for aberrant fetal growth and postnatal complications. Maternal obesity is associated with low birth weight (LBW) of piglets. However, the development of LBW from maternal obesity is not well understood. This study ...


Upregulation of angiostatic chemokines IP-10/CXCL10 and I-TAC/CXCL11 in human obesity and their implication for adipose tissue angiogenesis

24-May-2018 | Luisa Hueso; Rebeca Ortega; Francisca Selles; Ning Yun Wu-Xiong; Joaquin Ortega; Miguel Civera; Juan F Ascaso; Maria ..., International Journal of Obesity, 2018

Impaired angiogenesis is linked to adipose tissue (AT) dysfunction, inflammation, and insulin resistance in human obesity. Chemokine (C-X-C motif) receptor. (CXCR3) ligands are important regulators of angiogenesis in different disease contexts such as cancer; however, their role in human morbid ...


Impact of ambient air pollution on obesity: a systematic review

24-May-2018 | Ruopeng An; Mengmeng Ji; Hai Yan; Chenghua Guan, International Journal of Obesity, 2018

Over 80% of the global populations living in urban areas are exposed to air quality levels that exceed the World Health Organization limits. Air pollution may lead to unhealthy body weight through metabolic dysfunction, chronic disease onset, and disruption of regular physical activity. A ...


Epigallocatechin gallate targets FTO and inhibits adipogenesis in an mRNA m6A-YTHDF2-dependent manner

24-May-2018 | Ruifan Wu; Yongxi Yao; Qin Jiang; Min Cai; Qing Liu; Yizhen Wang; Xinxia Wang, International Journal of Obesity, 2018

N6-methyladenosine (m6A) modification of mRNA plays a role in regulating adipogenesis. However, its underlying mechanism remains largely unknown. Epigallocatechin gallate (EGCG), the most abundant catechin in green tea, plays a critical role in anti-obesity and anti-adipogenesis. High-performance ...


The case of GWAS of obesity: does body weight control play by the rules?

24-May-2018 | Manfred J. Müller; Corinna Geisler; John Blundell; Abdul Dulloo; Yves Schutz; Michael Krawczak; Anja Bosy-Westp ..., International Journal of Obesity, 2018

As yet, genome-wide association studies (GWAS) have not added much to our understanding of the mechanisms of body weight control and of the etiology of obesity. This shortcoming is widely attributed to the complexity of the issues. The appeal of this explanation notwithstanding, we surmise that ...


Are BMI and inflammatory markers independently associated with physical fatigability in old age?

24-May-2018 | Rachel Cooper; Maria Popham; Adam J Santanasto; Rebecca Hardy; Nancy W Glynn; Diana Kuh, International Journal of Obesity, 2018

Obesity and chronic low-grade inflammation have both been implicated in the onset of physical fatigue. However, few studies have investigated the independence of these associations in older community-dwelling populations. We therefore aimed to investigate the associations of body mass index (BMI) ...


Fate of the metabolically healthy obese—is this term a misnomer? A study from the Clinical Practice Research Datalink

17-May-2018 | Osama Moussa; Chanpreet Arhi; Paul Ziprin; Ara Darzi; Omar Khan; Sanjay Purkayastha, International Journal of Obesity, 2018

The metabolically healthy obese (MHO) phenotype may express typical characteristics on long-term follow-up. Little is known about the initiation of this phenotypes and its future stability. The Clinical Practice Research Datalink (CPRD) is a large-scale primary care database. The aim of this ...


Dietary protein intake in school-age children and detailed measures of body composition: the Generation R Study

17-May-2018 | Vincent Jen; Leonidas G. Karagounis; Vincent W. V. Jaddoe; Oscar H. Franco; Trudy Voortman, International Journal of Obesity, 2018

A high-protein diet in infancy increases the risk of obesity, but the effects of dietary protein intake in mid-childhood on body composition are unclear. Therefore, we studied associations of protein intake (total, animal and plant-sourced) at 8 years of age with anthropometric measures and body ...


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