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106 Newest Publications in bioscience horizons

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Isolation, identification and characterization of enzyme-producing lactic acid bacteria from traditional fermented foods

15-Jun-2018 | Ho J, Yin Sze L., Bioscience Horizons, 2018

Abstract Industrialization processes are prone to produce various forms of waste which can be utilized to produce silage. These wastes can be treated by using lactic acid bacteria (LAB), which are known to be potential enzyme producers. Seven strains of LAB were isolated from traditional ...

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In silico prediction of protein–protein interaction between Glossina m. morsitans (Westwood, 1851) and Trypanosoma brucei (Kinetoplastida: Trypanosomatidae)

15-Jun-2018 | Muriithi E, Kinyua J, Nyanjom S., Bioscience Horizons, 2018

Abstract Trypanosoma brucei is a pathogenic protozoa that causes chronic Human African Trypanosomiasis and African Animal Trypanosomiasis. The pathogenic parasite is transmitted to humans by the tsetse fly, Glossina m. morsitans. Trypanosomiasis control strategies have targeted either the tsetse ...

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Current research into the association between DNA copy number variation (CNV) and obesity

19-Oct-2017 | Shorter E., Bioscience Horizons, 2017

Abstract The analysis of human genomes has revealed an unexpectedly large variability among individuals of a population. This variation occurs via numerous different mechanisms and on many different scales, ranging from single nucleotide changes to the loss or gain of lengths of DNA encompassing ...

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Genetic polymorphisms as predictive markers for statin therapy: a route to improved cardiovascular patient outcomes?

22-Aug-2017 | Kansu BB., Bioscience Horizons, 2017

Abstract Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide. A significant risk factor for developing CVD is the presence of high plasma levels of low-density lipoprotein (LDL) cholesterol. With regard to pharmacological intervention, ‘fat busting’ statins are ...

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The application of magnetic nanoparticles in the treatment and monitoring of cancer and infectious diseases

09-Aug-2017 | Williams HM., Bioscience Horizons, 2017

Abstract Magnetic nanoparticles (MNPs) have shown promise in a number of biomedical applications, including: magnetic hyperthermia, enhancing magnetic resonance imaging (MRI) data, supplementing tissue engineering efforts and improving the delivery of drugs to difficult to reach microniches. ...

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The role of epigenetics in human evolution

28-Jul-2017 | Osborne A., Bioscience Horizons, 2017

Abstract This review aims to highlight the key areas in which changes to the epigenome have played an important role in the evolution and development of our species. Firstly, there will be a brief introduction into the topic of epigenetics to outline the current understanding of the subject and ...

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Changing Plastid Dynamics within Early Root and Shoot Apical Meristem-Derived Tissue of A. thaliana †

18-Feb-2017 | Bramham L., Bioscience Horizons, 2017

AbstractWhilst plastids are fundamental to many aspects of plant biology and the production of enhanced crop cultivars, research into the dynamics of non-green plastids has remained somewhat disregarded by the scientific community compared to chloroplasts. They are equally pivotal to normal plant ...

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Evolution of salivary secretions in haematophagous animals

14-Feb-2017 | Ware FL, Luck MR., Bioscience Horizons, 2017

AbstractHaemostasis is the prevention of blood fluidity in vertebrates and is the first stage of wound healing. Haematophagous animals use the blood of vertebrates as their sole source of nutrition and have evolved many salivary constituents to counteract the haemostatic response of their prey. ...

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Neural stem cell transplantation in ALS: developing a cure for the incurable?

29-Dec-2016 | Edwards A., Bioscience Horizons, 2016

AbstractAmyotrophic lateral sclerosis (ALS) is the most common motor neuron (MN) disease and usually causes death through respiratory muscle failure within 2–5 years of symptom onset, following progressive loss of function and considerable disability. Riluzole is currently the only ...

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Alzheimer's disease: the role of mitochondrial dysfunction and potential new therapies

29-Dec-2016 | Hawking ZL., Bioscience Horizons, 2016

AbstractAlzheimer's disease (AD) is characterized by neuronal loss and gradual cognitive impairment. AD is the leading cause of dementia worldwide and the incidence is increasing rapidly, with diagnoses expected to triple by the year 2050. Impaired cholinergic transmission is a major role player ...

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