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First Report of the Predominance of CC398 Staphylococcus aureus Strains in Osteomyelitis Complicating Diabetic Foot Ulcers: a national French study

Abstract

Staphylococcus aureus is the most common pathogen cultured from diabetic foot infection including diabetic foot osteomyelitis (DFOM). This French multicenter study determined the genetic content of S. aureus isolated from 157 consecutively cases admitted in 12 diabetic foot centres between 2008 and 2011. We describe for the first time the emergence of the CC398 methicillin‐susceptible S. aureus clone, the main clone in DFOM and its tropism for bone. This clone spreads to humans from animal source due to an intrinsic virulence. This adaptation of S. aureus isolates looks as a worrisome problem and should be carefully monitored.

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Authors:   Eric Senneville, Magali Brière, Chrystel Neut, Nourreddine Messad, Gérard Lina, Jean‐Louis Richard, Albert Sotto, Jean‐Philippe Lavigne,
Journal:   Clinical Microbiology and Infection
Year:   2013
Pages:   n/a
DOI:   10.1111/1469-0691.12375
Publication date:   28-Aug-2013
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