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A compact fiber-optic SHG scanning endomicroscope and its application to visualize cervical remodeling during pregnancy [Applied Physical Sciences]

We report the development of an all-fiber-optic scanning endomicroscope capable of high-resolution second harmonic generation (SHG) imaging of biological tissues and demonstrate its utility for monitoring the remodeling of cervical collagen during gestation in mice. The endomicroscope has an overall 2.0 mm diameter and consists of a single customized double-clad fiber,...

Authors:   Yuying Zhang; Meredith L. Akins; Kartikeya Murari; Jiefeng Xi; Ming-Jun Li; Katherine Luby-Phelps; Mala Mahendroo; Xingde Li
Journal:   Proceedings of the National Academy of Sciences current issue
Volume:   109
edition:   32
Year:   2012
Pages:   12878
DOI:   10.1073/pnas.1121495109
Publication date:   07-Aug-2012
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