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Phthalates are used as plasticizers in many commodities and materials. Therefore, they are found everywhere as contaminants in food and in environmental samples. Due to their potential for developmental and reproductive toxicity, some congeners pose a health risk for consumers and their use is legally restricted with bans and limits. This, however, applies only partly to their usage in cosmetics, toys and packaging materials. Phthalates used as plasticizers in cosmetic packaging could be a previously unknown source of exposure for consumers. In market surveys of the state laboratory of Basel-City, conspicuously high levels of di(2-ethylhexyl) phthalate (DEHP) and di-iso-nonyl phthalate (DINP) were found in shower and bath gels packed in soft PVC shaped as animals or fruits. The concentrations found ranged from 0.02 to 1.3%. It could be shown that concentrations increased significantly during storage. It can therefore be assumed that the phthalates found migrated from the packaging into the gels. The estimated exposure of adults and children to DEHP and DINP of 3.5 and 4.6 μg/kg bw/day, respectively, which may result when using the tested gels does not pose a health risk for the consumer (exposure value below TDI). Regarding the high background contamination levels with phthalates in other sources, exposure from cosmetics should be kept as low as possible. The establishment of limits for phthalates in cosmetics is discussed.
| Authors: | Judith P. Amberg-Müller, Urs Hauri, Urs Schlegel, Christopher Hohl, Beat J. Brüschweiler | |
| Journal: | Journal für Verbraucherschutz und Lebensmittelsicherheit | |
| Year: | 2010 | |
| DOI: | 10.1007/s00003-010-0620-0 | |
| Publication date: | 21-Jun-2010 |
Endothelial nitric oxide synthase polymorphism G298T in association with oxidative DNA damage in coronary atherosclerosis Content Type Journal Article Category Research Note Pages 1-4 DOI 10.1007/s12041-012-0183-1 Authors RAJESH G. KUMAR, Department of Genetics, Osmania Universi ... more
A micropropagation protocol was developed for multiplication of seedless lemon (Citrus limon L. cv. Kaghzi Kalan) using nodal explants. The maximum shoot regeneration was observed on low level of BAP (0.1 mg l−1) or kinetin (0.5 mg l−1). BA was recorded to be better than kinetin in terms of ... more
The objective of this study was to evaluate the activity, kinetic behavior, and thermal inactivation kinetics of peroxidase (POD) in aqueous extracts from two kinds of milk ripe stage corn, sweet corn and waxy corn. Optimum activities using guaiacol as the hydrogen donor were obtained for s ... more
New approach for the capture of tumor-derived exosomes from a prostate cancer cell line
Researchers at Washington State University report a new approach for the effective capture of tumor-derived exosomes from a prostate cancer cell line. Exosomes are small secreted vesicles that play a key role in intercellular communication and cancer progression. Developing effective and hi ... more
Nanoparticles hitchhiking their way along strands of hair
In shampoo ads, hair always looks like a shiny, smooth surface. But for physicists peering into microscopes, the hair surface looks much more rugged, as it is made of saw-tooth, ratchet-like scales. In a new theoretical study published, Matthias Radtke and Roland Netz have demonstrated that ... more
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