My watch list
my.bionity.com  
Login  

Marine Drugs, Vol. 16, Pages 218: The Positive Role of Curcumin-Loaded Salmon Nanoliposomes on the Culture of Primary Cortical Neurons

Marine Drugs, Vol. 16, Pages 218: The Positive Role of Curcumin-Loaded Salmon Nanoliposomes on the Culture of Primary Cortical Neurons

Marine Drugs doi: 10.3390/md16070218

Authors: Mahmoud Hasan Shahrzad Latifi Cyril J.F. Kahn Ali Tamayol Rouhollah Habibey Elodie Passeri Michel Linder Elmira Arab-Tehrany

Curcumin (diferuloylmethane) is a natural bioactive compound with many health-promoting benefits. However, its poor water solubility and bioavailability has limited curcumin’s biomedical application. In the present study, we encapsulated curcumin into liposomes, formed from natural sources (salmon lecithin), and characterized its encapsulation efficiency and release profile. The proposed natural carriers increased the solubility and the bioavailability of curcumin. In addition, various physico-chemical properties of the developed soft nanocarriers with and without curcumin were studied. Nanoliposome-encapsulated curcumin increased the viability and network formation in the culture of primary cortical neurons and decreased the rate of apoptosis.

Authors:   Hasan, Mahmoud ; Latifi, Shahrzad ; Kahn, Cyril J.F.; Tamayol, Ali ; Habibey, Rouhollah ; Passeri, Elodie ; Linder, Michel ; Arab-Tehrany, Elmira
Journal:   Marine Drugs
Volume:   16
edition:   7
Year:   2018
Pages:   218
DOI:   10.3390/md16070218
Publication date:   25-Jun-2018
Facts, background information, dossiers
  • water
  • neurons
  • nanocarriers
  • liposomes
  • lecithin
  • Formation
More about Molecular Diversity Preservation International
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE