FGF signaling deregulation is associated with early developmental skeletal defects in animal models for mucopolysaccharidosis type II (MPSII)

Isolation, identification and characterization of enzyme-producing lactic acid bacteria from traditional fermented foods

Abstract Industrialization processes are prone to produce various forms of waste which can be utilized to produce silage. These wastes can be treated by using lactic acid bacteria (LAB), which are known to be potential enzyme producers. Seven strains of LAB were isolated from traditional fe ... more

In silico prediction of protein–protein interaction between Glossina m. morsitans (Westwood, 1851) and Trypanosoma brucei (Kinetoplastida: Trypanosomatidae)

Abstract Trypanosoma brucei is a pathogenic protozoa that causes chronic Human African Trypanosomiasis and African Animal Trypanosomiasis. The pathogenic parasite is transmitted to humans by the tsetse fly, Glossina m. morsitans. Trypanosomiasis control strategies have targeted either the t ... more

Erratum to “N-Acetyl-2-Aminofluorene (AAF) Processing in Adult Rat Hepatocytes in Primary Culture Occurs by High-Affinity Low-Velocity and Low-Affinity High-Velocity AAF Metabo ...

The above mentioned articles were inadvertently switched in the May 2018 issue of Toxicological Sciences (Volume 163, Number 1). The pagination details have now been corrected in the final versions of these articles (https://doi.org/10.1093/toxsci/kfy006; https://doi.org/10.1093/toxsci/kfy0 ... more

A dominant evolutionary theme emerges to better predict clinical outcomes for cancer

Despite the decades long battle since the 'war on cancer' was first declared, major breakthroughs toward improving clinical outcomes have remained elusive. Now, with advanced sequencing, scientists have increasingly entered the fray from an evolutionary perspective toward cancer in the hope ... more

High doses of antibiotics may have the potential to promote increased cross-resistance

Antibiotic resistance has become an increasing public health concern, with MRSA infections and last lines of antibiotic drug treatments having to be increasingly deployed in hospitals and clinics. In Molecular Biology and Evolution, Oz, et. al., utilized an experimental evolution approach t ... more

New sequencing tools give up close look at yeast evolution

The baker's yeast Saccharomyces cerevisiae has been associated with human activities for thousands of years, being the primary biological agent in baking, brewing, winemaking and other fermentation processes. It is also one of the most important model organisms in molecular biology and gene ... more