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Does nonmetastatic castration-resistant prostate cancer still exist?

Does nonmetastatic castration-resistant prostate cancer still exist?

Does nonmetastatic castration-resistant prostate cancer still exist?, Published online: 23 April 2018; doi:10.1038/s41571-018-0025-z

After almost 20 years of negative trials of novel therapies for patients with nonmetastatic castration-resistant prostate cancer (nmCRPC), two androgen receptor antagonists have shown favourable outcomes in phase III trials involving patients with high-risk nmCRPC. Herein, the history of nmCRPC and clinical trials in this disease setting are discussed and a perspective on molecular imaging and clinical management of nmCRPC is offered.

Authors:   Celestia S. Higano
Journal:   Nature Clinical Practice Oncology
Volume:   15
edition:   6
Year:   2018
Pages:   350
DOI:   10.1038/s41571-018-0025-z
Publication date:   23-Apr-2018
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