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DNA methylation as a genomic marker of exposure to chemical and environmental agents

Publication date:

August 2018


Source:Current Opinion in Chemical Biology, Volume 45

Author(s): Richard R Meehan, John P Thomson, Antonio Lentini, Colm E Nestor, Sari Pennings

Recent progress in interpreting comprehensive genetic and epigenetic profiles for human cellular states has contributed new insights into the developmental origins of disease, elucidated novel signalling pathways and enhanced drug discovery programs. A similar comprehensive approach to decoding the epigenetic readouts from chemical challenges in vivo would yield new paradigms for monitoring and assessing environmental exposure in model systems and humans.





Authors:   Author(s): Richard R Meehan, John P Thomson, Antonio Lentini, Colm E Nestor, Sari Pennings
Journal:   Current Opinion in Chemical Biology
Volume:   45
Year:   2018
Pages:   48
DOI:   10.1016/j.cbpa.2018.02.006
Publication date:   15-Apr-2018
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