My watch list  

Neurons that drive and quench thirst

Thirst is a vital primordial emotion that motivates fluid intake to compensate for incessant water loss incurred as a result of breathing, sweating, and urine production. Indeed, the maintenance of adequate hydration is a prerequisite for life and, accordingly, the desire to drink emerges as soon as the body's water content declines by 1 to 2%, and this feeling intensifies progressively with further depletion ( 1 – 3 ). Although regions in the brain that are critical for water intake have been known for more than 60 years, the identification and functional analysis of thirst-related neurons only became possible with the recent advent of genetically targeted photoactivation and photometry, methods that respectively allow manipulation and monitoring of electrical activity in vivo, using fiber-optic microprobes ( 4 – 7 ). On page 1149 of this issue, Allen et al. ( 8 ) reveal the existence of neurons that specifically encode the intensity and aversive quality of thirst within the median preoptic nucleus (MnPO) of the hypothalamus.

Authors:   Claire Gizowski; Charles W. Bourque
Journal:   Science
Volume:   357
edition:   6356
Year:   2017
Pages:   1092
DOI:   10.1126/science.aao5574
Publication date:   15-Sep-2017
Facts, background information, dossiers
  • water
  • neurons
  • production
More about Science International / AAAS
  • Publications

    Random number generators go public

    On 10 July, researchers in Chile will unveil an online public random number service. Later in July, the U.S. National Institute of Standards and Technology (NIST) will launch its Randomness Beacon as a permanent service, upgrading a pilot program that began in 2013. Brazil, too, is planning ... more

    When the cure kills—CBD limits biodiversity research

    The Convention on Biological Diversity (CBD) commits its 196 nation parties to conserve biological diversity, use its components sustainably, and share fairly and equitably the benefits from the utilization of genetic resources. The last of these objectives was further codified in the Conve ... more

    See-through solar cells could power offices

    Solar windows turn some of the light shining through into electricity. They've been on the market for years. But many of these windows absorb some visible light, leaving them with a reddish or brownish hue, a trait frowned on by architects. Now, new versions are on the way that absorb invis ... more

  • News

    Merck Named a Top Employer by Science Magazine

    Merck announced it was ranked fourth among biotechnology and pharmaceutical companies worldwide by Science magazine, a leading peer-reviewed international scientific publication. This ranking marks the fourth year in a row Merck was named one of the top 20 employers in the healthcare and li ... more

    Merck Named as Top Employer by Science Magazine

    Merck announced it was named number 11 among the top 20 employers in the global biopharmaceutical industry by Science magazine, a leading peer-reviewed international scientific publication. This is the third year in a row that Merck, including EMD Serono in the United States, has been named ... more

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE