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Diabetic wound regeneration using peptide-modified hydrogels to target re-epithelialization [Applied Biological Sciences]

There is a clinical need for new, more effective treatments for chronic wounds in diabetic patients. Lack of epithelial cell migration is a hallmark of nonhealing wounds, and diabetes often involves endothelial dysfunction. Therefore, targeting re-epithelialization, which mainly involves keratinocytes, may improve therapeutic outcomes of current treatments. In this study,...

Authors:   Yun Xiao; Lewis A. Reis; Nicole Feric; Erica J. Knee; Junhao Gu; Shuwen Cao; Carol Laschinger; Camila Londono; Julia Antolovich; Alison P. McGuigan; Milica Radisic
Journal:   Proceedings of the National Academy of Sciences current issue
Volume:   113
edition:   40
Year:   2016
Pages:   E5792
DOI:   10.1073/pnas.1612277113
Publication date:   04-Oct-2016
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