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7 Current news about the topic velcade

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Janssen-Cilag International NV withdraws its application for an extension of the indication for Velcade (bortezomib)

05-Jul-2012

The European Medicines Agency has been formally notified by Janssen-Cilag International NV of its decision to withdraw its application for an extension of the therapeutic indication for the centrally authorised medicine Velcade (bortezomib).On 2 September 2011, Janssen-Cilag International NV ...

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Anti-cancer activity of BioInvent's BI-505 demonstrated in animal model

15-Dec-2011

BioInvent International AB announced that new preclinical data has been presented on its BI-505 programme that demonstrates anti-cancer activity in multiple myeloma and beneficial effect on bone density. The results were presented at the American Society of Hematology (ASH) Annual Meeting.The ...

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Aeterna Zentaris Receives Positive Scientific Advice for its Phase 3 Trial with Perifosine in Colorectal Cancer

01-Jul-2010

Aeterna Zentaris Inc. announced that it has received positive Scientific Advice from the European Medicines Agency (EMA) regarding the Phase 3 trial initiated last April for the development of its lead anticancer proprietary compound, perifosine, in refractory advanced colorectal cancer. The ...

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TopoTarget and CuraGen Initiate Phase II Trial of Belinostat (PXD101) in Combination with Velcade

30-Mar-2007

TopoTarget A/S and CuraGen Corporation announced the initiation of patient dosing in a Phase II open-label, multi-center clinical trial evaluating the efficacy and safety of intravenous belinostat (PXD101), a small molecule histone deacetylase (HDAC) inhibitor, in combination with Velcade® ...

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CuraGen and TopoTarget Initiate Clinical Program Evaluating Oral Administration of PXD101

Phase I trial to establish the dose and frequency for oral PXD101 in patients with advanced solid tumors

14-Aug-2006

CuraGen Corporation and TopoTarget A/S announced the initiation of a Phase I clinical trial evaluating the administration of oral PXD101, a small molecule histone deacetylase (HDAC) inhibitor, in patients with advanced solid tumors. The Phase I trial will be led by Dr. W. Kevin Kelly, Associate ...

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CuraGen and TopoTarget Initiate NCI-sponsored Phase I Clinical Trial of PXD101 and Azacitidine

10-Aug-2006

CuraGen Corporation and TopoTarget A/S announced the initiation of patient dosing in a Phase I clinical trial evaluating the safety and tolerability of PXD101, a small molecule histone deacetylase (HDAC) inhibitor, in combination with azacitidine for the treatment of advanced hematologic ...

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CuraGen and TopoTarget Initiate Phase Ib/II Clinical Trial with PXD101 and Velcade(R) for Multiple Myeloma

24-Mar-2006

CuraGen Corporation and TopoTarget A/S announced the initiation of patient dosing in a Phase Ib/II proof-of-concept trial to evaluate PXD101, a small molecule histone deacetylase (HDAC) inhibitor, in combination with Velcade(R) (bortezomib) for the treatment of relapsed, refractory multiple ...

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