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62 Current news about the topic neurodegenerative disorders


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Protein complex prevents toxic aggregation of proteins


A protein complex within the cell has been found to play a key role in preventing the toxicity of proteins which build up amyloid plaques and can lead to neurodegenerative disorders such as Alzheimer’s and Huntington’s disease. Researchers from the Universities of Konstanz (Germany), Leeds (UK) ...


Immune system reveals new ways to treat brain disease and pain


Boosting the immune system could offer a radical new way to treat Alzheimer’s disease, according to Dr Michal Schwartz from the Weizmann Institute of Science in Israel. Experiments in mice have shown that targeting immune cells arrested the damage to the brain and helped preserve cognition. For ...


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Eating more fish could prevent Parkinson's disease

Parvalbumin found to prevent amyloid formation


A new study from Chalmers University of Technology, Sweden, shines more light on the link between consumption of fish and better long-term neurological health. Parvalbumin, a protein found in great quantities in several different fish species, has been shown to help prevent the formation of ...


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Brain fights West Nile Virus in unexpected way


In a turnabout, a biochemical self-destruct trigger found in many other types of cells appears to guard the lives of brain cells during an infection with West Nile virus. UW Medicine scientists led research showing that this chemical pathway doesn't have to sacrifice brain cells to destroy the ...


Rescue protein gives doomed cells a stay of 'execution'


A research team led by St. Jude Children's Research Hospital immunologists has discovered how a set of proteins delays the "executioner" machinery that kills damaged or infected cells in a process called necroptosis. The scientists believe the finding may have wide clinical implications if ...


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A glitch in 'gatekeeper cells' slowly suffocates the brain


Abnormality with special cells that wrap around blood vessels in the brain leads to neuron deterioration, possibly affecting the development of Alzheimer's disease, a USC-led study reveals. "Gatekeeper cells" called pericytes surround blood vessels. They contract and dilate to control blood flow ...


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Promising discovery for a non-invasive early detection of Alzheimer's disease


A discovery of high relevance in medical research will be published in Journal of Alzheimer's Disease, entitled "Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer's Disease". The paper stems from a fruitful collaboration between the neuroscience laboratory from the ...


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The molecular roots of Alzheimer's


Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer's disease. Knowing the shape of the molecule -- and how that shape may be disrupted by certain genetic mutations -- can help in understanding how ...


PhoreMost Ltd and University of Cambridge collaborate

Identifying innovative drug targets for neurodegenerative disease


PhoreMost Ltd (PhoreMost), a biopharmaceutical company dedicated to drugging ‘undruggable’ disease targets, has entered into a research collaboration with the laboratory of Professor David Rubinsztein at the University of Cambridge. The groups will study and translate essential cellular ...


Ancient anti-inflammatory drug salicylic acid has cancer-fighting properties


Scientists from the Gladstone Institutes have identified a new pathway by which salicylic acid--a key compound in the nonsteroidal anti-inflammatory drugs aspirin and diflunisal--stops inflammation and cancer. In a study, the researchers found that both salicylic acid and diflunisal suppress two ...


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