Molecular mechanism of a rare disease causing severe immunodeficiencies deciphered
It is WHIM syndrome, a disease caused by mutations in a cell membrane receptor.
25-May-2022 -
WHIM syndrome is a congenital disease that causes severe immunodeficiency and increased infections, both bacterial and viral. This syndrome is caused by mutations in the CXCR4 gene, a receptor involved in cell adhesion and migration, among other functions, but until now it was unknown how these ...
cell migration
congenital diseases
immunodeficiency
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