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25 Current news about the topic migraine

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Addex Successfully Completes ADX48621 Phase I Program

30-Jan-2009

Addex Pharmaceuticals announced the successful completion of two Phase I studies of a newly developed modified release formulation of ADX48621. The studies showed that ADX48621, a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM) in development for Parkinson's ...

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Phase II Results of COL-144 Presented at European Headache and Migraine Trust International Congress 2008

Results Demonstrate Safety and Efficacy of First-in-Class Neurally

09-Sep-2008

CoLucid Pharmaceuticals, Inc., announced Phase II results of its lead compound COL-144 in the treatment of acute migraine. Results demonstrated that COL-144 was safe and effective in relieving migraine headaches. COL-144 is a first-in-class Neurally Acting Anti-Migraine Agent (NAAMA), which ...

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BTG plc commences first clinical study of novel migraine treatment

01-Feb-2008

BTG plc announced that BGC20-1531, a potential treatment for migraine headaches, has commenced clinical development. Dosing has begun in a randomised, double-blind, placebo controlled phase I study, which will assess the safety, tolerability and pharmacokinetic profile of single rising doses of ...

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Addex Announces ADX10059 Phase IIa Acute Anxiety Data

04-Jan-2008

Addex Pharmaceuticals announced that ADX10059 did not reduce acute anticipatory anxiety in a small Phase IIa study in patients with dental anxiety. However, some signs of anxiolytic activity were observed. Development of ADX10059 for gastroesophageal reflux disease (GERD) and migraine is ...

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Addex commences Phase II clinical trials programme compound ADX10059 for use against migraine and anxiety

04-Sep-2006

Addex Pharmaceuticals announced the start of the Phase II development programme of its lead compound ADX10059. This announcement follows the successful completion of three Phase I trials, in over 100 healthy subjects, which demonstrated good tolerability of the compound across a broad dose range. ...

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