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26 Current news about the topic migraine


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Addex' ADX10059 has potential for Parkinson's disease levodopa induced dyskinesia (PD-LID)


Addex Pharmaceuticals reported that its lead product, ADX10059, which is nearing completion of Phase IIb testing in gastroesophageal reflux disease (GERD) and migraine prevention, also has demonstrated significant potential in a non-human primate model of Parkinson's disease levodopa induced ...


Addex Successfully Completes ADX48621 Phase I Program


Addex Pharmaceuticals announced the successful completion of two Phase I studies of a newly developed modified release formulation of ADX48621. The studies showed that ADX48621, a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM) in development for Parkinson's ...


Phase II Results of COL-144 Presented at European Headache and Migraine Trust International Congress 2008

Results Demonstrate Safety and Efficacy of First-in-Class Neurally


CoLucid Pharmaceuticals, Inc., announced Phase II results of its lead compound COL-144 in the treatment of acute migraine. Results demonstrated that COL-144 was safe and effective in relieving migraine headaches. COL-144 is a first-in-class Neurally Acting Anti-Migraine Agent (NAAMA), which ...


BTG plc commences first clinical study of novel migraine treatment


BTG plc announced that BGC20-1531, a potential treatment for migraine headaches, has commenced clinical development. Dosing has begun in a randomised, double-blind, placebo controlled phase I study, which will assess the safety, tolerability and pharmacokinetic profile of single rising doses of ...


Addex Announces ADX10059 Phase IIa Acute Anxiety Data


Addex Pharmaceuticals announced that ADX10059 did not reduce acute anticipatory anxiety in a small Phase IIa study in patients with dental anxiety. However, some signs of anxiolytic activity were observed. Development of ADX10059 for gastroesophageal reflux disease (GERD) and migraine is ...


Addex commences Phase II clinical trials programme compound ADX10059 for use against migraine and anxiety


Addex Pharmaceuticals announced the start of the Phase II development programme of its lead compound ADX10059. This announcement follows the successful completion of three Phase I trials, in over 100 healthy subjects, which demonstrated good tolerability of the compound across a broad dose range. ...


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