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149 Current news about the topic melanoma

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Increased eye cancer risk linked to pigmentation genes that dictate eye color

22-Aug-2016

New research links specific inherited genetic differences (alterations) to an increased risk for eye (uveal) melanoma, a rare form of melanoma that arises from pigment cells that determine eye color. Roughly 2,500 people are diagnosed with uveal melanoma in the United States annually. Previous ...

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Natural killer cells have a memory

09-Jun-2016

Researchers at the University of Bonn and the Ludwig-Maximilians-Universität of Munich have decoded a new mechanism of how the immune system can specifically attack pigmented cells of the skin. It was previously believed that natural killer cells did not have an immunological memory for the ...

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Cholesterol-lowering drug kills melanoma cells - If messenger substance is present

07-Jun-2016

Special cholesterol-lowering drugs can hamper the growth of metastasising melanoma cells if the cellular messenger substance Interleukin-6 (IL-6) is present. This link was observed in a research project funded by the Austrian Science Fund FWF. In laboratory tests, statins (cholesterol-lowering ...

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Two-drug immunotherapy deemed safe for lung cancer patients

03-Jun-2016

Small cell lung cancer (SCLC) represents approximately 14 percent of all types of lung cancer. Many patients with SCLC respond to initial chemotherapy; however, they eventually relapse and develop progressive disease that has no effective treatment options. A new Moffitt Cancer Center study being ...

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Skin cancer teams up with Sonic the Hedgehog

10-Mar-2016

Basal cell carcinoma (also known as basalioma or basal cell cancer -- BCC) is the most common, and the 5th expensive cancer type to cure, making about 90% of malignant skin tumors. Among risk factors there are genetic malfunctions, appearance of freckles, x-rays and radiation, burns or use of ...

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Mutation of BAP1 gene passed down over centuries

24-Dec-2015

University of Hawai'i Cancer Center researchers discovered members of four families, apparently unrelated and living in different states across the US, shared the identical mutation of a gene called BAP1 that causes mesothelioma, melanoma, renal carcinoma and other cancers. This raised two ...

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Nanotech drug delivery shows promise for improved melanoma treatment

11-Dec-2015

Researchers have developed a new three-drug delivery system for cancer treatment, especially metastatic melanoma, the deadliest form of skin cancer - and shown that the system may have particular value with cancers like this that often spread through the lymphatic system. The new technology takes ...

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New class of inhibitory compounds developed to aid melanoma treatments

04-Dec-2015

A University of California, Irvine pharmacology researcher has helped create a class of inhibitory compounds that can strongly enhance the effect of anti-tumor drugs for melanoma. In doing so, Daniele Piomelli, the Louise Turner Arnold Chair in the Neurosciences at UCI, and scientists at the ...

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TAK-733 shows challenge of using a promising drug in the human body

15-Oct-2015

A University of Colorado Cancer Center study reports "robust antitumor activity" of the drug TAK-733 in cells and mouse models of colorectal cancer. In all, 42 of 54 tested cell lines were sensitive to the drug, as were 15 of 20 tumors grown on mice from patient samples. Nine of these ...

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New treatment for advanced melanoma

Opdivo offers treatment option for patients with poor prognosis

28-Apr-2015

The European Medicines Agency (EMA) has recommended granting a marketing authorisation for Opdivo (nivolumab). Opdivo is recommended to be used on its own (monotherapy) for the treatment of adult patients with advanced (unresectable or metastatic) melanoma.For decades, chemotherapy was the ...

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