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29 Current news about the topic gene expression analysis


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Machine-learning driven findings uncover new cellular players in tumor microenvironment

Involvement of adipocytes in nivolumab response in ipilimumab resistant melanoma patients


New findings presented by CytoReason reveals possible new cellular players in the tumor microenvironment that could impact the treatment process for the most in-need patients - those who have already failed to respond to ipilimumab (anti-CTLA4) immunotherapy. Once validated, the findings could ...


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New software processes huge amounts of single-cell data

Comprehensive analysis of large gene-expression datasets


Scientists from the Helmholtz Zentrum München have developed a program that is able to help manage enormous datasets. The software, named Scanpy, is a candidate for analyzing the Human Cell Atlas. “It’s about analyzing gene-expression data of a large number of individual cells,” explains lead ...


Shedding light on protein interaction networks in a developing organism


Researchers succeeded for the first time in mapping protein-protein interactions in living developing plant roots. The findings were made by three international research groups led by the department of Plant Developmental Biology at Wageningen University and Research. The work is considered a ...


Breast cancer: finding the smoking gun

A new method developed at Vanderbilt may help “inventory” all tumor-promoting genes.


Many genes are associated with cancer. The trick is proving they actually promote tumor formation. One approach, detailed by Ian Macara , Ph.D., and colleagues is an in vivo “gain-of-function” screen. The researchers used a gene “library” (complementary DNA carried by lentivirus) to increase the ...


The gene that turns ponies into large horses

TiHo researchers discover genetic causes of the body sizes of horses


Ponies have a maximum height of 148 centimetres. When the height at the withers is greater, they are deemed to be large horses. Scientists at the Institute for Animal Breeding and Genetics at University of Veterinary Medicine Hannover (TiHo) have investigated genetic causes for different body ...


Epistem's Biomarker Division Gains GCLP Accreditation


Epistem plc has announced that their Biomarker Division has been awarded Good Clinical Laboratory Practice (GCLP) accreditation status. The Biomarker Division conducts gene expression analysis to support clinical drug development programs within pharmaceutical and biotechnology organisations, ...


OncoMed Pharmaceuticals and Fluidigm annouce strategic collaboration


OncoMed Pharmaceuticals, Inc. and Fluidigm Corporation announced a new initiative to apply Fluidigm’s microfluidic tools to the analysis of tumor cell heterogeneity, including cancer stem cells. The collaboration will combine Fluidigm’s microfluidic platforms with OncoMed’s proprietary cancer ...


Stratagene and Merck Subsidiary, Rosetta Inpharmatics, enter into joint development and license agreement

Development of RNA Purification System for Use in Molecular Diagnostics and Research Applications


Stratagene Corporation has entered into a joint development and license agreement with Rosetta Inpharmatics LLC, a wholly-owned subsidiary of Merck & Co., Inc., to create an automated solution for the isolation of nucleic acids from a variety of clinical samples. Nucleic acid purification allows ...


Gene Logic Provides the FDA with Access to Toxicogenomics Data and Analysis Systems


Gene Logic Inc. announced that it entered into an agreement with the United States Food and Drug Administration ("FDA") to provide the FDA with access to certain of Gene Logic's genomics data and software, including: - an extensive collection of toxicogenomics and rat classical toxicology data ...


Sigma-Aldrich Announces Service Provider for Whole Genome Amplification Technology


Sigma-Aldrich announced MOgene, LC as its first service provider of the GenomePlex® Whole Genome Amplification (WGA) technology. This follows a recent licensing agreement with Rubicon Genomics, allowing Sigma to offer GenomePlex Whole Genome Amplification kits to service providers. MOgene, LC is ...


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