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93 Current news about the topic dna repair


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Key player in cell metabolism identified


Researchers from the Genomic Instability and Cancer Laboratory at Institute for Research in Biomedicine (IRB Barcelona) have identified a key role for EXD2 in protein production in the mitochondria, the cellular organelles responsible for the majority of energy generation. "We have provided ...


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Solving of a decade long mystery could help in fight against TB


Scientists have solved a decade-old mystery that could eventually lead to the development of earlier treatments for one of the world's deadliest diseases, which affects up to 2 billion people. Research carried out by the University of Sussex and the Polish Academy of Sciences has identified two ...


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How DNA damage turns immune cells against cancer


Cancer is essentially a disease of the cell replication cycle. The goal of treating the disease is to permanently kill off the cells that replicate with abandon without any molecular brakes. Chemotherapy and radiation cause breaks in DNA, and eventually, death even in these out-of-control cells. ...


Why do BRCA1 mutations cause predominantly breast and ovarian cancer?


The human body holds many mysteries, and function of the BRCA1 gene is among them. Women who inherit a faulty copy of BRCA1 have up to a 65 percent chance to develop breast cancer by age 70. They also have up to a 39 percent chance to develop ovarian cancer. Rong Li, Ph.D., and colleagues at The ...


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The fork in the road to DNA repair


The human body consists of trillions of cells, and within each are billions of DNA molecules. Strict maintenance of the molecules is essential to maintain a healthy cell and thus a healthy body. This maintenance is challenged by the daily bombardment of chemicals, UV light, radical oxgen and ...


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How are long strands of DNA packed into tiny cells?


Scientists are a step closer to understanding how DNA, the molecules that carry all of our genetic information, is squeezed into every cell in the body. How DNA is "packaged" in cells influences the activity of our genes and our risk for disease. Elucidating this process will help researchers in ...


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New instruction manual to repair broken DNA uncovered


Drexel University and Georgia Institute of Technology researchers have discovered how the Rad52 protein is a crucial player in RNA-dependent DNA repair. The results of their study reveal a surprising function of the homologous recombination protein Rad52. They also may help to identify new ...


Fish oil component helps damaged brain and retina cells survive


A team of researchers led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, has shown for the first time that NDP1, a signaling molecule made from DHA, can trigger the production of a protective protein ...


Merck Licenses Four Oncology Research and Development Programs from Vertex

Vertex receives upfront payment of $230 million plus royalties on future sales


Merck announced that it has entered into a licensing agreement with Vertex Pharmaceuticals Inc. for the worldwide development and commercialization of four promising research and development programs that represent novel approaches to the treatment of cancer.“With this strategic deal we ...


BioMed X and Merck start new project in cancer research


BioMed X and Merck announce the start of a new research group at the BioMed X Innovation Center in Heidelberg. The new project entitled “DNA Damage in Cancer” represents an extension of their ongoing collaboration in the field of oncology research. The aim of this new research team is to develop ...


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