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281 Current news about the topic degenerative disorder

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New method reveals how the Parkinson's disease protein damages cell membranes

The method makes it possible to study tiny quantities of biological molecules without using fluorescent markers

03-Jul-2020

In sufferers of Parkinson's disease, clumps of α-synuclein (alpha-synuclein), sometimes known as the 'Parkinson's protein', are found in the brain. These destroy cell membranes, eventually resulting in cell death. Now, a new method developed at Chalmers University of Technology, Sweden, reveals ...

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Cleaning craze in the brain

Synaptic protein waste" was collected more quickly when the presynaptic protein bassoon is missing

28-May-2020

Synapses consist of hundreds of different proteins. For correct transmission of brain signals, their building blocks must constantly be checked for functionality and replaced by new ones. A team of researchers from the Leibniz Institute of Neurobiology Magdeburg, the German Centre for ...

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Innovative ways to battle Parkinson’s disease

New radiotracer for differential diagnostics

28-Feb-2020

An interdisciplinary team from the Institute of Radiopharmaceutical Cancer Research headed by Prof. Peter Brust has won HZDR’s (Helmholtz-Zentrum Dresden-Rossendorf) third Innovation Contest. The researchers succeeded in developing a new substance that could improve image-based differential ...

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Therapies without drugs

Chips and bids taking the place of pills and meds

27-Feb-2020

Fraunhofer researchers are investigating the potential of microimplants to stimulate nerve cells and treat chronic conditions like asthma, diabetes, or Parkinson’s disease. Find out what makes this form of treatment so appealing and which challenges the researchers still have to master. A study ...

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Molecular bodyguards against Parkinson’s disease

06-Dec-2019

Chaperone proteins in human cells dynamically interact with the protein α-Synuclein, which is strongly associated with Parkinson’s disease. A disturbed relationship to these “bodyguards” leads to cell damage and the formation of Lewy bodies typical for Parkinson’s disease. Parkinson’s disease is ...

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Better biosensor technology created for stem cells

Technology may help guide treatment of Alzheimer's, Parkinson's diseases

13-Nov-2019

A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders. The technology, which features a unique graphene and gold-based platform and high-tech imaging, monitors ...

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How CRISPR can help fight against neurodegenerative diseases

Scientists listed ways of applying genetic engineering to treat Parkinson's disease

12-Sep-2019

Researchers of Sechenov University and University of Pittsburgh described the most promising strategies in applying genetic engineering for studying and treating Parkinson's disease. This method can help evaluate the role of various cellular processes in pathology progression, develop new drugs ...

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Breakthrough Prize 2020 for biochemist Hartl and geneticist Horwich

09-Sep-2019

F.-Ulrich Hartl, Director at the Max Planck Institute of Biochemistry in Martinsried, is awarded the Breakthrough Prize in Life Sciences 2020 together with Arthur L. Horwich of Yale School of Medicine/HHMI. They are honored for discovering functions of molecular chaperones in mediating protein ...

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Research into Parkinson’s disease: binding-protein prevents fibril proliferation

04-Sep-2019

Several neurodegenerative diseases such as Parkinson’s are closely linked to the aggregation of a specific protein, α-synuclein. An international collaborative project involving Heinrich Heine University Düsseldorf (HHU), Forschungszentrum Jülich (FZJ) and RWTH Aachen University has now shed ...

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Assemblies of proteins relevant not only for Alzheimer’s and Parkinson’s disease

23-Aug-2019

Amyloid fibrils play a crucial role in neurodegenerative illnesses. Scientists from Heinrich Heine University Düsseldorf (HHU) and Forschungszentrum Jülich have now been able to use cryo-electron microscopy (cryo-EM) to decode the spatial structure of the fibrils that are formed from PI3K SH3 ...

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