Awakening to new drugs against sleeping sickness
Structure–activity relationships and optimization of triazine nitriles as rhodesain inhibitors
21-May-2013 -
Sleeping sickness kills tens of thousands of people in Africa each year. Current chemotherapies are subject to various limitations, including resistance. Rhodesain, an enzyme of the parasites that cause this illness (human African trypanosomiasis), has emerged as a target for new drug candidates. ...
Hoffmann-La Roche
inhibitors
Roche
+2