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Malaria pathogens under the X-ray microscope

X-ray microscopy at BESSY II reveals how antimalaria-drugs might work

04-Nov-2019

Malaria is one of the most threatening infectious diseases in the world. An international team has now been able to investigate malaria pathogens in red blood cells in vivo using the BESSY II X-ray microscope and the ALBA and ESRF synchrotron sources. The scientists reveal the mechanisms used by ...

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The immune system's fountain of youth

Helping the immune system clear away old cells in aging mice helped restore youthful characteristics

03-Jan-2019

If only we could keep our bodies young, healthy and energetic, even as we attain the wisdom of our years. New research at the Weizmann Institute of Science suggests this dream could be at least partly obtainable in the future. The results of this research, led by Prof. Valery Krizhanovsky and Dr. ...

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Lego proteins revealed

25-Aug-2017

When hemoglobin undergoes just one mutation, these protein complexes stick to one another, stacking like Lego blocks to form long, stiff filaments. These filaments, in turn, elongate the red blood cells found in sickle-cell disease. For over 50 years, this has been the only known textbook example ...

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Making spines from sea water

10-Apr-2017

Some sea creatures cover themselves with hard shells and spines, while vertebrates build skeletons out of the same minerals. How do these animals get the calcium they need to build these strong mineral structures? Professors Lia Addadi and Steve Weiner of the Weizmann Institute of Science's ...

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DNA dominos on a chip

Carriers of genetic information packed together on a biochip like in nature

11-Aug-2016

Normally, individual molecules of genetic material repel each other. However, when space is limited DNA molecules must be packed together more tightly. This case arises in sperm, cell nuclei and the protein shells of viruses. An international team of physicists has now succeeded in artificially ...

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Eating air, making fuel

27-Jun-2016

All life on the planet relies, in one way or another, on a process called carbon fixation: the ability of plants, algae and certain bacteria to "pump" carbon dioxide (CO2) from the environment, add solar or other energy and turn it into the sugars that are the required starting point needed for ...

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Making the most of a shitty situation

What the “fecal prints” of microbes can tell us about Earth’s evolution

02-Jan-2015

Everything that eats must excrete, and microbes are no exception. Microbes have dominated the Earth’s ecology for at least the past 3.5 billion years. They play a vital role in the planet’s carbon cycle by digesting organic matter. So their waste potentially carries information about how the ...

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New hope for Gaucher patients

21-Jan-2014

What causes brain damage and inflammation in severe cases of Gaucher disease? Little is known about the events that lead to brain pathology in some forms of the disease, and there is currently no treatment available – a bleak outlook for sufferers and their families. Now, scientists at the ...

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Not so dumb

A new kind of genetic switch can target the activities of just one type of brain cell

27-Nov-2013

Mysterious brain cells called microglia are starting to reveal their secrets thanks to research conducted at the Weizmann Institute of Science. Until recently, most of the glory in brain research went to neurons. For more than a century, these electrically excitable cells were believed to perform ...

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Tokyo Institute of Technology research: Towards medical treatments using cell level control

06-Nov-2012

Researchers at Tokyo Institute of Technology and the Weizmann Institute of Science identify a means of controlling biological processes that could help treatments for immune disease, neurological disorders and cancer.The cellular response to a number of signals including inflammatory cytokines, ...

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