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Scientists sharpen their molecular scissors and expand the gene editing toolbox


Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have figured out a better way to deliver a DNA editing tool to shorten the presence of the editor proteins in the cells in what they describe as a "hit and run" approach. CRISPR (clustered regularly interspaced short palindromic ...


Model of tumor spreading may help doctors pinpoint best treatment


Advances in personalized medicine allow doctors to select the most promising drugs for certain types of malignant tumors. But what if before initiating treatment, they could go a step further and use a mini-model of the human body to see how each patient's actual tumor responds to the drugs and ...


Scientists prove feasibility of 'printing' replacement tissue


Using a sophisticated, custom-designed 3D printer, regenerative medicine scientists at Wake Forest Baptist Medical Center have proved that it is feasible to print living tissue structures to replace injured or diseased tissue in patients. The scientists said they printed ear, bone and muscle ...


New nanotechnology detects biomarkers of cancer


Researchers at Wake Forest Baptist Medical Center have developed a new technology to detect disease biomarkers in the form of nucleic acids, the building blocks of all living organisms. The proof-of-concept study is published in the journal Nano Letters. "We envision this as a potential ...


The role DNA methylation plays in aging cells


Although every person's DNA remains the same throughout their lives, scientists know that it functions differently at different ages. As people age, drastic changes occur in their DNA methylation patterns, which are thought to act as a "second code" on top of the DNA that can lock genes in the on ...


Stem cells in urine easy to isolate and have potential for numerous therapies


Could harvesting stem cells for therapy one day be as simple as asking patients for a urine sample? Researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine and colleagues have identified stem cells in urine that can be directed to become multiple cell types. "These ...


Migraine triggers tricky to pinpoint

Too many variables exist, says new research from Wake Forest Baptist


Women often point to stress, hormones, alcohol, or even the weather as possible triggers for their migraines. But a new study from Wake Forest Baptist Medical Center found that it is nearly impossible for patients to determine the true cause of their migraine episodes without undergoing formal ...


Study shows community approach effective in fight against diabetes


New research from Wake Forest Baptist Medical Center shows that a diabetes prevention program led by community health workers is effective at reducing blood glucose and potentially reducing diabetes over the long term. This is the largest program to successfully replicate the results achieved by ...


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