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106 Current news of University of Michigan

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Missing link in coronavirus jump from bats to humans could be pangolins, not snakes

31-Mar-2020

As scientists scramble to learn more about the SARS-CoV-2 coronavirus, two recent studies of the virus' genome reached controversial conclusions: namely, that snakes are intermediate hosts of the new virus, and that a key coronavirus protein shares "uncanny similarities" with an HIV-1 protein. ...

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The danger behind certain biologics

The surprising role of an immune cell that explains some of the drugs' side effects

16-Dec-2019

Autoimmune disorders such as rheumatoid arthritis, psoriasis, and Crohn's disease plague tens of millions of Americans and are the result of the body's immune system, whose role is to fight against disease-causing pathogens, turning against itself. Thankfully, several new drugs designed to fight ...

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Implantable cancer traps could provide earlier diagnosis

04-Nov-2019

Invasive procedures to biopsy tissue from cancer-tainted organs could be replaced by simply taking samples from a tiny "decoy" implanted just beneath the skin, University of Michigan researchers have demonstrated in mice. These devices have a knack for attracting cancer cells traveling through ...

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Blood biopsy: New technique enables detailed genetic analysis of cancer cells

17-May-2019

A new way to cleanly separate out cancer cells from a blood sample enables comprehensive genetic profiling of the cancer cells, which could help doctors target tumors and monitor treatments more effectively. It is a dramatic improvement over current approaches because it also encompasses the ...

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How signals get inside cancer cells and spur aggressive growth

15-May-2018

The outside of a cancer cell is bombarded by signals. They come from the immune system, supporting tissues and other structures. But how do those signals impact cancer? A new study provides a surprising model of the process by which those signals enter and influence the cell. The finding could ...

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Initial step of photosynthesis observed

Charge seperation in pigments with 2D electronic spectroscopy unveiled

22-Mar-2018

Photosynthesis has driven life on this planet for more than 3 billion years -- first in bacteria, then in plants -- but we don't know exactly how it works. Now, a University of Michigan biophysicist and her group have been able to image the moment a photon sparks the first energy conversion steps ...

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Nanodiscs catch misfolding proteins red-handed

19-Dec-2017

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins when they are most toxic, detailing them down to the atomic ...

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Kevlar-based artificial cartilage mimics the magic of the real thing

17-Nov-2017

The unparalleled liquid strength of cartilage, which is about 80 percent water, withstands some of the toughest forces on our bodies. Synthetic materials couldn't match it -- until "Kevlartilage" was developed by researchers at the University of Michigan and Jiangnan University. "We know that we ...

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Biocatalysts are a bridge to greener, more powerful chemistry

15-Nov-2017

New research from the University of Michigan Life Sciences Institute is building a bridge from nature's chemistry to greener, more efficient synthetic chemistry. Researchers in the lab of Alison Narayan analyzed biocatalysts evolved by nature for their effectiveness in a variety of synthetic ...

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Fighting cancer with cancer: 3-D cultured cells could drive precision therapy

10-Nov-2017

Honeycomb-like arrays of tiny, lab-grown cancers could one day help doctors zero in on individualized treatments for ovarian cancer, an unpredictable disease that kills more than 14,000 women each year in the United States alone. A team of researchers has devised a process that can grow hundreds ...

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