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19 Current news of University of Maryland

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New technique breaks through a technology roadblock that limited RNA imaging for 50 years

Researchers develop tools to sharpen 3D view of large RNA molecules

14-Oct-2020

University of Maryland scientists have developed a method to determine the structures of large RNA molecules at high resolution. The method overcomes a challenge that has limited 3D analysis and imaging of RNA to only small molecules and pieces of RNA for the past 50 years. The new method, which ...

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Better Than Cyclodextrins

Molecular Containers for the Sequestration of Neurotransmitter Drugs in Water

19-Jun-2020

Molecular containers that remove drugs, toxins, or malodorous substances from the environment are called sequestering agents. Scientists have developed a class of molecular containers that specifically sequester neurotransmitter antagonists. The barrel-shaped molecules called Pillar[n]MaxQ bind ...

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Scientists discover hidden differences among cells that may help them evade drug therapy

12-Sep-2019

University of Maryland researchers have discovered that seemingly identical cells can use different protein molecules to carry out the same function in an important cellular process. The scientists named this newly discovered variability "functional mosaicism," and it has significant implications ...

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Experimental noninvasive tool monitors effectiveness of stem cell transplantation

24-May-2019

Stem-cell based therapies to strengthen the heart muscle and treat other diseases are beginning to show promise in human clinical trials. However, other than observing clinical outcomes, lack of a repeatable, time-sensitive and noninvasive tool to assess the effectiveness of the transplanted ...

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How the food we eat affects biochemical signals in the gut

07-Jun-2018

For years, researchers have studied how the body's microbiome impacts virtually every aspect of human health ranging from the immune system to mental wellness. Now, a recent study led by a multi-institutional research team, including the University of Maryland, several institutions in South ...

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Two Group A Streptococcus genes linked to 'flesh-eating' bacterial infections

26-Sep-2017

Group A Streptococcus bacteria cause a variety of illnesses that range from mild nuisances like strep throat to life-threatening conditions including pneumonia, toxic shock syndrome and the flesh-eating disease formally known as necrotizing fasciitis. The life-threatening infections occur when ...

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Napping flies have higher resistance to deadly human pathogen

30-Mar-2017

A new University of Maryland study has found that fruit flies genetically coded to take frequent naps had the strongest resistance to both a fungal infection and to a bacteria that the World Health Organization says is one of the world's most dangerous superbugs for humans. Researchers study the ...

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New method enables creation of better therapeutic antibodies

15-Mar-2017

Antibodies are the foot soldiers of our immune system. These specialized, Y-shaped proteins attach to bacteria and viruses, where they either block the pathogen's activity directly, or signal the immune system's cells to destroy the invader. The second function--the ability to target invaders for ...

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Has HDL, the 'good' cholesterol, been hyped?

12-May-2016

For years, physicians have told patients that HDL (high-density lipoprotein cholesterol) helps protect them from cardiovascular disease (CVD). And the higher the number, the more the protection. HDL, often considered an independent predictor of heart disease, has been dubbed the "good" ...

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Test detects signs of Lyme disease near time of infection

16-Feb-2016

When it comes to early diagnosis of Lyme disease, the insidious tick-borne illness that afflicts about 300,000 Americans annually, finding the proverbial needle in the haystack might be a far easier challenge--until now, perhaps. An experimental method developed by federal and university ...

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