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Reactivating Aging Stem Cells in the Brain

With increasing age, and in patients suffering from Alzheimer’s disease, the hippocampus’ ability to create new neurons declines steadily – and with it, its memory functions


As people get older, their neural stem cells lose the ability to proliferate and produce new neurons, leading to a decline in memory function. Researchers at the University of Zurich have now discovered a mechanism linked to stem cell aging – and how the production of neurons can be ...


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Smartphone App to Change Your Personality

Can personality traits such as openness, conscientiousness, or sociability be psychologically influenced in a short-term and targeted manner?


How quickly can personality traits be modified? An international research team led by the University of Zurich has shown that daily use of a smartphone app can lead to desired personality changes within three months. And three months after the daily interventions, the changes are still ...


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1918 Pandemic Second Wave Had Fatal Consequences

History repeats itself


In the event of a pandemic, delayed reactions and a decentralized approach by the authorities at the start of a follow-up wave can lead to longer-lasting, more severe and more fatal consequences, researchers from the universities of Zurich and Toronto have found. The interdisciplinary team ...


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Risk-Taking Linked to Particular Brain Features

Several influencing factors studied in combination for the first time


There is a common genetic and neurobiological basis for risky behavior – the genetic disposition for risk-taking is mapped in several areas of the brain, a UZH study shows. The study combines genetic information and brain scans from more than 25,000 people for the first time. Risky behaviors such ...


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Genetic Engineering without Unwanted Side-Effects Helps Fight Parasites

A live vaccine for toxoplasmosis


Modified CRISPR-Cas9 gene editing scissors are enabling researchers at UZH to make alterations to the genetic material of single-cell organisms that are indistinguishable from natural mutations. This method is making it possible to develop a (harmless) experimental live vaccine for the widespread ...


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Good immune defenses come with a risk of multiple sclerosis

How genetic predisposition contributes to the development of the autoimmune disease multiple sclerosis in combination with environmental factors


About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study led by the University of Zurich has now shown how this genetic predisposition contributes to the development of the autoimmune disease multiple sclerosis in combination with environmental factors. The ...


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Hedonism Leads to Happiness

The capacity to experience pleasure or enjoyment without getting distracted by intrusive thoughts contributes at least as much to a happy and satisfied life as successful self-control


Relaxing on the sofa or savoring a delicious meal: Enjoying short-term pleasurable activities that don’t lead to long-term goals contributes at least as much to a happy life as self-control, according to new research from the University of Zurich and Radboud University in the Netherlands. The ...


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Blueprint of Oxytocin Receptor Facilitates Development of New Autism Drugs


Oxytocin plays a role in various mental health and sexual reproduction disorders. Researchers at the University of Zurich have now determined the three-dimensional structure of the oxytocin receptor to which the hormone binds. This knowledge could promote the development of novel drugs to treat a ...


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Genetic Malfunction of Brain Astrocytes Triggers Migraine

Cingulate cortex may represent a critical hub in the disease


Neuroscientists of the University of Zurich shed a new light on the mechanisms responsible for familial migraine: They show that a genetic dysfunction in specific brain cells of the cingulate cortex area strongly influences head pain occurrence. Migraine is one of the most disabling disorders, ...


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Mapping Immune Cells in Brain Tumors

Composition of the immune cells of various types of brain tumors with unparalleled precision described


It is not always possible to completely remove malignant brain tumors by surgery so that further treatment is necessary. Researchers from the University of Zurich and the University Hospital Zurich have now been able to describe, with unparalleled precision, the composition of the immune cells of ...


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