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Simple and Fast Method for Radiolabelling Antibodies against Breast Cancer

Using UV light, radiolabelled antibodies can be produced in just 15 minutes

24-Apr-2019

Radioactive antibodies that target cancer cells are used for medical diagnostics with PET imaging or for targeted radioimmunotherapy. Researchers from the University of Zurich have created a new method for radiolabelling antibodies using UV light. In less than 15 minutes, the proteins are ...

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Precise Decoding of Breast Cancer Cells Creates New Option for Treatment

17-Apr-2019

Researchers at the University of Zurich and from IBM Research have investigated the varying composition of cancer and immune cells in over one hundred breast tumors. They've found that aggressive tumors are often dominated by a single type of tumor cell. If certain immune cells are present as ...

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New Potential Approach to Treat Atopic Dermatitis

19-Mar-2019

How does the immune system respond to fungi on our skin? Researchers at the University of Zurich have demonstrated that the same immune cells that protect us against skin fungi also encourage the inflammatory symptoms of atopic dermatitis. An antibody therapy could alleviate this chronic ...

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Bat Influenza Viruses Could Infect Humans

22-Feb-2019

Bats don’t only carry the deadly Ebola virus, but are also a reservoir for a new type of influenza virus. These newly discovered flu viruses could potentially also attack the cells of humans and livestock, researchers at the University of Zurich have now shown. Seasonal outbreaks of the flu are ...

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How Type 1 Diabetes Gradually Destroys Insulin Production

04-Feb-2019

Using the new Imaging Mass Cytometry method, Zurich researchers have investigated the pancreas of healthy organ donors and those with type 1 diabetes. The study shows that many beta cells, which normally produce insulin, are still present in the early stages of the disease, but look very ...

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Potential for risky behavior is also in your genes

15-Jan-2019

As part of an international research project, a group of scientists from the University of Zurich found genetic variants associated with risk tolerance and risky behaviors. It is one of the first studies to link genetic variants with behavioral outcomes, which are relevant to social science ...

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How Drugs Can Minimize the Side Effects of Chemotherapy

11-Jan-2019

Researchers at the University of Zurich have determined the three-dimensional structure of the receptor that causes nausea and vomiting as a result of cancer chemotherapy. The study explains for the first time why some drugs work particularly well in ameliorating these side effects. The results ...

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From Receptor Structure to New Osteoporosis Drugs

22-Nov-2018

Researchers at the University of Zurich have determined the three-dimensional structure of a receptor that controls the release of calcium from bones. The receptor is now one of the main candidates for developing new drugs to treat osteoporosis. Knowing the receptor's blueprint will be ...

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Insect Antibiotic Provides New Way to Eliminate Bacteria

16-Nov-2018

An antibiotic called thanatin attacks the way the outer membrane of Gram-negative bacteria is built. Researchers at the University of Zurich have now found out that this happens through a previously unknown mechanism. Thanatin, produced naturally by the spined soldier bug, can therefore be used ...

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Larvae Help in Search for Appetite Suppressants

Zebrafish as a novel testing system for psychoactive substances

02-Nov-2018

Researchers at the University of Zurich and Harvard University have developed a new strategy in the search for psychoactive drugs. By analyzing the behavior of larval zebrafish, they can filter out substances with unwanted side effects right from the start. This method has resulted in the ...

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