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More Selective Elimination of Leukemia Stem Cells and Blood Stem Cells

Novel immunotherapy: Genetically modified immune cells attack cancer cells

12-May-2020

Hematopoietic stem cells from a healthy donor can help patients suffering from acute leukemia. However, the side effects of therapies are often severe. A group of researchers led by the University of Zurich have now shown how human healthy and cancerous hematopoietic stem cells can be more ...

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Lipid Metabolism Controls Brain Development

Diminished stem cell activity reduces cognitive performance

11-May-2020

A lipid metabolism enzyme controls brain stem cell activity and lifelong brain development. If the enzyme does not work correctly, it causes learning and memory deficits in humans and mice, as researchers at the University of Zurich have discovered. Regulating stem cell activity via lipid ...

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Are the high prices of cancer drugs justified?

Does the cost correspond to the particular drug’s effectiveness in combating the disease?

05-May-2020

Do high prices of some cancer medicines have a higher benefit than those drugs with lower prices? An international UZH study has concluded that, in general, there is no correlation between costs of a cancer drugs and their clinical benefit. The researchers are therefore calling for the clinical ...

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Blocking the Iron Transport Could Stop Tuberculosis

02-Apr-2020

The bacteria that cause tuberculosis need iron to survive. Researchers at the University of Zurich have now solved the first detailed structure of the transport protein responsible for the iron supply. When the iron transport into the bacteria is inhibited, the pathogen can no longer grow. This ...

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Loss of Protein Disturbs Intestinal Homeostasis and Can Drive Cancer

20-Mar-2020

An international team of researchers from the University of Zurich, the University Hospital Zurich, Heidelberg and Glasgow has identified a novel function for the cell death regulating protein MCL1: It is essential in protecting the intestine against cancer development – independent of ...

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Producing Human Tissue in Space

Low Earth Orbit as a future research, development and production location?

10-Mar-2020

The University of Zurich has sent adult human stem cells to the International Space Station (ISS). Researchers from UZH Space Hub will explore the production of human tissue in weightlessness. On 6 March at 11:50 p.m. EST, the International Space Station resupply mission Space X CRS-20 took off ...

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Refining Breast Cancer Classification by Multiplexed Imaging

22-Jan-2020

An imaging approach developed at UZH enables the study of breast cancer tissue in greater detail. It uses 35 biomarkers to identify the different cell types in breast tumors and its surrounding area compared to the current standard of testing single markers. This increases the precision of tumor ...

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Newly Discovered Protein Gives Signal for Virus Infection

19-Dec-2019

Researchers at the University of Zurich have discovered a protein that enables adenoviruses to infect human cells. The Mib1 protein gives the virus the signal to uncoat the DNA and release it into the nucleus. Blocking this protein could therefore help people with weakened immune systems to fight ...

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New Approach to Treating Incurable Leukemia in Children Discovered

26-Nov-2019

Acute lymphoblastic leukemia is the most common form of cancer affecting children in Switzerland and, unfortunately, is often incurable. Researchers from the University of Zurich and the University Children’s Hospital Zurich have now found a way to stop the driving force behind this type of ...

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Trust in Science and Research Remains High

Science Barometer Switzerland

07-Nov-2019

The Swiss population’s trust in science and research is high to very high. As the Science Barometer Switzerland 2019 study shows, people in Switzerland have a positive attitude towards science and are keen to receive information about research, with climate and energy considered the most ...

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