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75 Current news of Universität Bonn

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Should I or shouldn't I?

Nerve cell activity shows how confident we are

13-Oct-2020

The activity of individual nerve cells in the brain tells us how confident we are in our decisions. This is shown by a recent study by researchers at the University of Bonn. The result is unexpected - the researchers were actually on the trail of a completely different evaluation mechanism. You ...

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New method allows precise gene control by light

Study enhances research toolbox with a new tool with great potential

02-Oct-2020

A novel optical switch makes it possible to precisely control the lifespan of genetic "copies". These are used by the cell as building instructions for the production of proteins. The method was developed by researchers from the universities of Bonn and Bayreuth. It may significantly advance the ...

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Blood breakdown product commandeers important enzyme

Unexpected interaction between the protein APC and heme discovered

08-Sep-2020

The hemoglobin in the red blood cells ensures that our body cells receive sufficient oxygen. When the blood pigment is broken down, "heme" is produced, which in turn can influence the protein cocktail in the blood. Researchers at the University of Bonn have now discovered in complex detective ...

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Fat crystals trigger chronic inflammation

Scientists identify previously unknown disease mechanism

28-Aug-2020

A congenital disorder of the fat metabolism can apparently cause chronic hyperreaction of the immune system. This is the conclusion reached by researchers from the University of Bonn in a recent study. The results are published in the journal Autophagy. Some individuals suffer from a genetic ...

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Genetic cause of congenital malformation discovered

Study reveals that genetic information controls development of the urinary tract, rectum and genitals

10-Aug-2020

Spontaneous mutations of a single gene are likely to cause serious developmental disorders of the excretory organs and genitalia. This is shown in an international study led by the University of Bonn and published in the journal "Frontiers in Cell and Developmental Biology". The researchers also ...

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Receptor makes mice strong and slim

The corresponding signaling pathways might also exist in humans

29-Jun-2020

Increasing abdominal girth and shrinking muscles are two common side effects of aging. Researchers at the University of Bonn have discovered a receptor in mice that regulates both effects. Experiments with human cell cultures suggest that the corresponding signaling pathways might also exist in ...

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Tuberculosis vaccine strengthens immune system

How BCG vaccination reduces susceptibility to other infections

17-Jun-2020

A tuberculosis vaccine developed 100 years ago also makes vaccinated persons less susceptible to other infections. While this effect has been recognized for a long time, it is not known what causes it. Together with colleagues from Australia and Denmark, researchers from Radboud university ...

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Platelets exacerbate immune response

Clotting cells are also an important regulator of inflammation

14-May-2020

Platelets not only play a key role in blood clotting, but can also significantly intensify inflammatory processes. This is shown by a new study carried out by scientists from the University of Bonn together with colleagues from Sao Paulo (Brazil). In the medium term, the results could open up new ...

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A "corset" for the enzyme structure

Structure of biocatalysts depends on whether they are in cells or in the test tube

29-Apr-2020

The structure of enzymes determines how they control vital processes such as digestion or immune response. This is because the protein compounds are not rigid, but can change their shape through movable "hinges". The shape of enzymes can depend on whether their structure is measured in the test ...

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How cells recognize uninvited guests

16-Apr-2020

Until now, the immune sensor TLR8 has remained in the shadows of science. A research team led by the University of Bonn has now discovered how this sensor plays an important role in defending human cells against intruders. The enzymes RNaseT2 and RNase2 cut ribonucleic acids (RNAs) of bacteria ...

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