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Covid vaccination improves effectiveness of cancer treatment

Clinical study on nasopharyngeal cancer with unexpected result

14-Nov-2022

Patients with nasopharyngeal cancer are often treated with drugs that activate their immune system against the tumor. Until now, it was feared that vaccination against Covid-19 could reduce the success of cancer treatment or cause severe side effects. A recent study by the Universities of Bonn ...

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Hemophilia: Training the immune system to be tolerant

Study elucidates an important immune mechanism

02-Nov-2022

Hemophilia A is the most common severe form of hemophilia. It affects almost exclusively males. The disease can usually be treated well, but not for all sufferers. A study at the University of Bonn has now elucidated an important mechanism that is crucial for making the therapy effective. The ...

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Newly discovered process brings immune cells up to speed

Study identifies mechanism otherwise found in metastasizing cancer cells

18-Oct-2022

Cancer cells use an unusual mechanism to migrate into new tissue and form metastases there. The same process probably also keeps some immune cells on their toes. This is the result of a recent study led by the University of Bonn. According to the study, certain structures, the centrioles, ...

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1 million-year-old marine DNA found in Antarctic sediment

New technique helps decipher ‘who’ has lived in the ocean in the past and ‘when’

06-Oct-2022

A new study led by the University of Tasmania – with the participation of the University of Bonn – discovered the oldest marine DNA in deep-sea sediments of the Scotia Sea north of the Antarctic continent. The material could be dated to one million years. Such old material demonstrates that ...

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Fish to help in search for MS drugs

Study follows an innovative path in the search for new active substances

22-Sep-2022

The zebrafish serves as a model organism for researchers around the world: it can be used to study important physiological processes that also take place in a similar form in the human body. It is therefore routinely used in the search for possible active substances against diseases. Researchers ...

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Moss repair team also works in humans

"If we could correct faulty sites in the genetic code with RNA editing methods, this would potentially also offer starting points for the treatment of hereditary diseases"

21-Sep-2022

If everything is to run smoothly in living cells, the genetic information must be correct. But unfortunately, errors in the DNA accumulate over time due to mutations. Land plants have developed a peculiar correction mode: they do not directly improve the errors in the genome, but rather ...

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DNA guardians out of control

Our own immune system can become the enemy when mechanisms that are actually protective get out of control

29-Aug-2022

In ANCA-associated vasculitis, excessive inflammatory reactions lead to pulmonary hemorrhages that can be fatal if left untreated. Researchers at the University of Bonn, together with colleagues from Germany, the Netherlands, Switzerland and England, have deciphered a mechanism in mice and ...

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Therapeutic drug renders cancer cell weapon harmless

Already approved drug could pave way to new pharmaceuticals

26-Aug-2022

Many tumor cells mist themselves with a protective perfume that disables the immune system. But a drug already approved for other purposes can apparently render this weapon harmless. This is shown in a study by the University of Bonn and the University Medical Center Hamburg-Eppendorf, which has ...

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Many paths are open to neurons born early

The time of birth of neurons determines what they can become

18-Aug-2022

When it comes to royalty, things are clear: The monarch's first child inherits the crown. Siblings born later must make do with a less glamorous profession. This is quite similar for some nerve cells in the brain. In their case, it is not the order in which they are born, but at least the time of ...

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Covid-19: New energy for flagging immune cells

Hope for new treatment options

29-Jul-2022

In severe Covid-19 patients, the metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively. Perhaps this finding explains why ...

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