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163 Current news of Universität Basel

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Making cancer stem cells visible to the immune system

New results may enable innovative treatment concept against leukemia

19-Jul-2019

Leukemia stem cells protect themselves against the immune defense by suppressing a target molecule for killer cells. This protective mechanism can be tricked with drugs. In the journal "Nature", scientists from Basel, Tübingen and Heidelberg describe the new therapeutic approaches that can ...

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Speed controllers for protein production

15-Jul-2019

The translation of the genetic code into proteins is a vital process in any cell. Prof. Mihaela Zavolan’s team at the Biozentrum, University of Basel, has now uncovered important factors that influence the speed of protein synthesis in the cell. The results, recently published in “PNAS”, serve as ...

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Neuronal Parkinson inclusions are different than expected

Study raises new questions about the etiology of Parkinson’s disease

27-Jun-2019

An international team of researchers involving members of the University of Basel’s Biozentrum challenges the conventional understanding of the cause of Parkinson’s disease. The researchers have shown that the inclusions in the brain’s neurons, characteristic of Parkinson‘s disease, are comprised ...

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Learning from Nature’s Bounty: New Libraries for Drug discovery

12-Jun-2019

Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult to emulate and build on Nature’s success in the laboratory. By ...

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Creating blood vessels on demand

Researchers discover new cell population that can help in regenerative processes

05-Apr-2019

When organs or tissues are damaged, new blood vessels must form as they play a vital role in bringing nutrients and eliminating waste and it is necessary for organs and tissues to regain their normal function. At present, the injection of growth factors or genetic material into the tissue site of ...

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Crime Scene Schizophrenia – 30 Genes under suspicion

01-Apr-2019

The research group led by Prof. Alex Schier, Director of the University of Basel’s Biozentrum, has identified 30 genes associated with schizophrenia. The team was able to show which pathological changes in the brain and behavioral abnormalities are triggered by these genes. The research team led ...

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Sound the alarm! How injured plant cells warn their neighbors

26-Mar-2019

All organisms can be injured. But what happens when a plant is injured? How can it heal itself and avoid infections? An international research team from the University of Basel and Ghent University has reported on wound reaction mechanisms in plants in the journal Science. Their insights into ...

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Stress hormones promote breast cancer metastasis

14-Mar-2019

It has long been thought that stress contributes to cancer progression. Scientists from the University of Basel and the University Hospital of Basel have deciphered the molecular mechanisms linking breast cancer metastasis with increased stress hormones. In addition, they found that synthetic ...

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Cryo-force spectroscopy reveals the mechanical properties of DNA components

12-Feb-2019

Physicists from the University of Basel have developed a new method to examine the elasticity and binding properties of DNA molecules on a surface at extremely low temperatures. With a combination of cryo-force spectroscopy and computer simulations, they were able to show that DNA molecules ...

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Escort service: The role of immune cells in the formation of metastases

08-Feb-2019

Tumor cells use a certain type of immune cells, the so-called neutrophils, to enhance their ability to form metastases. Scientists have deciphered the mechanisms of this collaboration and found strategies for blocking them. This is reported by researchers from the University of Basel and the ...

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