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Cellular nanosponges could soak up SARS-CoV-2

A nanoparticle decoy with the virus' natural targets lure SARS-CoV-2 away from cells

22-Jun-2020

Scientists are working overtime to find an effective treatment for COVID-19, the illness caused by the new coronavirus, SARS-CoV-2. Many of these efforts target a specific part of the virus, such as the spike protein. Now, researchers reporting in Nano Letters have taken a different approach, ...

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Machine learning technique speeds up crystal structure determination

04-Feb-2020

Nanoengineers at the University of California San Diego have developed a computer-based method that could make it less labor-intensive to determine the crystal structures of various materials and molecules, including alloys, proteins and pharmaceuticals. The method uses a machine learning ...

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Autonomous Microtrap for Pathogens

Self-propelled onion-like microvehicle can attract, trap, and destroy biological threats

03-Feb-2020

Antibiotics are more efficient when they can act on their target directly at the site of infestation, without dilution. In the journal Angewandte Chemie, American scientists describe a synthetic chemical trap that propels itself to its place of action in the body fluid and then lures the bacteria ...

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Machine learning algorithm can't distinguish these lab mini-brains from preemie babies

03-Sep-2019

Brain organoids -- also called mini-brains -- are 3D cellular models that represent aspects of the human brain in the laboratory. Brain organoids help researchers track human development, unravel the molecular events that lead to disease and test new treatments. They aren't prefect replicas, of ...

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Evonik intensifies commitment to microbiome research

Three-year partnership with the University of California San Diego Center for Microbiome Innovation

30-Aug-2019

Human skin is home to a large number and wide variety of microorganisms such as bacteria, fungi, and viruses, collectively known as the skin microbiome. Its composition is as individual as a fingerprint and depends on a variety of factors. This new partnership between Evonik and the University of ...

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Next-generation gene drive arrives

CRISPR-based 'allelic drive' allows genetic editing with selective precision and broad implications

11-Apr-2019

New CRISPR-based gene drives and broader active genetics technologies are revolutionizing the way scientists engineer the transfer of specific traits from one generation to another. Scientists at the University of California San Diego have now developed a new version of a gene drive that opens ...

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An errant editing enzyme promotes tumor suppressor loss and leukemia propagation

08-Jan-2019

Researchers at University of California San Diego School of Medicine report that detection of "copy editing" by a stem cell enzyme called ADAR1, which is active in more than 20 tumor types, may provide a kind of molecular radar for early detection of malignancies and represent a new therapeutic ...

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Taking out the (life-threatening) garbage

Bacteria eject trash to survive

28-Sep-2018

Scientists have known for decades that certain bacteria produce small spherical versions of themselves. Although they lack basic materials to reproduce or function like normal cells, recent interest in such "minicells" has spiked due to their proficiency as nano-sized delivery tools for drugs and ...

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'Building up' stretchable electronics to be as multipurpose as your smartphone

16-Aug-2018

By stacking and connecting layers of stretchable circuits on top of one another, engineers have developed an approach to build soft, pliable "3D stretchable electronics" that can pack a lot of functions while staying thin and small in size. As a proof of concept, a team led by the University of ...

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Why are neuron axons long and spindly?

They're optimizing signaling efficiency!

16-Jul-2018

A team of bioengineers at UC San Diego has answered a question that has long puzzled neuroscientists, and may hold a key to better understanding the complexities of neurological disorders: Why are axons, the spindly arms extending from neurons that transmit information from neuron to neuron in ...

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