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Benzene in cherry flavor - where it comes from and how to avoid it?

Flavorings containing benzaldehyde can develop benzene under the influence of light

30-Mar-2020

In 2013, the Stiftung Warentest found harmful benzene in drinks with cherry flavor. But how did the substance get into the drinks? Was the source benzaldehyde, an essential component of the cherry flavoring? And if so, how could the problem be solved? A new study by the Leibniz-Institute for Food ...

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Blocking sugar structures on viruses and tumor cells

Artificial sugar-binding protein may inhibit cell growth

19-Mar-2020

During a viral infection, viruses enter the body and multiply in its cells. Viruses often specifically attach themselves to the sugar structures of the host cells, or present characteristic sugar structures on their surface themselves. Researchers at the Technical University of Munich (TUM) have ...

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A molecular map for the plant sciences

First comprehensive map of the proteome of the model plant Arabidopsis thaliana

16-Mar-2020

Plants are essential for life on earth. They provide food for essentially all organisms, oxygen for breathing, and they regulate the climate of the planet. Proteins play a key role in controlling all aspects of life including plants. Under the leadership of the Technical University of Munich ...

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Fatal overproduction of antibodies

Mutations in plasma cells play a key role in light chain amyloidosis

11-Mar-2020

Bone marrow plasma cells produce antibodies. These comprise two long and two short protein chains. The pathological proliferation of plasma cells can lead to an overproduction of the short chains. These associate to fibrils and deposit in organs. The result is fatal organ failure. A research team ...

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Safe from over- or underdosing

Long-lasting and precise dosing of medication thanks to an oil-hydrogel mixture

24-Feb-2020

Using a mixture of oil droplets and hydrogel, medical active agents can be not only precisely dosed, but also continuously administered over periods of up to several days. The active agents inside the active droplets are released at a constant rate, decreasing the risk of over- or ...

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Transparent human organs allow 3D maps at the cellular level

17-Feb-2020

For the first time, researchers managed to make intact human organs transparent. Using microscopic imaging they could revealed underlying complex structures of the see-through organs at the cellular level. Resulting organ maps can serve as templates for 3D-bioprinting technologies. In the future, ...

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Gene scissors against incurable muscular disease

New gene correction therapy

30-Jan-2020

Duchenne type muscular dystrophy (DMD) is the most common hereditary muscular disease among children. A Munich based team has developed a gene therapy that may provide permanent relief for those suffering from DMD. LMU researcher Eckhard Wolf was involved in the study. Muscles need dystrophin in ...

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A real alternative to crude oil

The synthesis of bio-based high-performance polyamide from biogenic residues

29-Jan-2020

A research team from the Fraunhofer Society and the Technical University of Munich (TUM) led by chemist Volker Sieber has developed a new polyamide family which can be produced from a byproduct of cellulose production – a successful example for a more sustainable economy with bio-based ...

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Emergence of calorie burning fat cells

A new approach to treating overweight and obesity

10-Jan-2020

1.9 billion people in the world are overweight. Of these, 650 million people are obese, which increases the risk of secondary diseases such as high blood pressure or cancer. Professor Martin Klingenspor and his team at the Technical University of Munich (TUM) examine how our fat metabolism ...

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Looking at the good vibes of molecules: a new method for label-free metabolic imaging

09-Jan-2020

Label-free dynamic detection of biomolecules is a major challenge in live-cell microscopy. The simultaneous visualization of dynamic alterations for classes of metabolites, such as carbohydrates and lipids, was an unmet need in biomedical research. Now, a novel imaging method developed by a ...

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