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New applications for organoids from human intestinal tissue

An alternative to animal experiments

15-Oct-2020

Researchers of the Technical University of Munich (TUM) have cultured so-called intestinal organoids from human intestinal tissue, which is a common byproduct when performing bowel surgery. These small “miniature intestines” can be used for molecular biological examinations and allow for a direct ...

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3D images display plant organs down to the smallest detail

Intelligent software for a better understanding of plant tissue development

01-Oct-2020

Using artificial intelligence, researchers have developed a novel computer-based image processing method for plant sciences. The method enables the detailed 3D representation of all cells in various plant organs with unprecedented precision. Plant organs, such as the root, the shoot axis, the ...

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Secure nano-carrier delivers medications directly to cells

Nanoparticles with synthetic DNA can control release of drugs

30-Sep-2020

Medications often have unwanted side-effects. One reason is that they reach not only the unhealthy cells for which they are intended, but also reach and have an impact on healthy cells. Researchers at the Technical University of Munich (TUM), working together with the KTH Royal Institute of ...

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“Honey, I shrunk the detector”

Researchers have developed the world’s smallest ultrasound detector

18-Sep-2020

Researchers at Helmholtz Zentrum München and the Technical University of Munich (TUM) have developed the world’s smallest ultrasound detector. It is based on miniaturized photonic circuits on top of a silicon chip. With a size 100 times smaller than an average human hair, the new detector can ...

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"Biohackers" TV series stored on DNA

Synthetic genetic material as a stable storage medium - for over 1000 years

03-Sep-2020

The first episode of the newly released series "Biohackers" was stored in the form of synthetic DNA. This was made possible by the research of Prof. Reinhard Heckel of the Technical University of Munich (TUM) and his colleague Prof. Robert Grass of ETH Zürich. They have developed a method that ...

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Designed bacteria produce coral-antibiotic

Sustainable biotechnological production of a natural substance against tuberculosis

19-Aug-2020

Corals growing on the reefs of the Bahamas produce an active agent that kills multi-resistant tuberculosis bacteria. Scientists at the Technical University of Munich (TUM) have managed to produce the antibiotic biotechnologically in the laboratory – fast, cost-efficient and sustainably. Thomas ...

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Grow faster, die sooner

How growth rates influence the fitness of bacteria: Antibiotic therapy with a carrot and a stick?

10-Aug-2020

Bacteria are survival artists: When they get nutrition, they multiply rapidly, albeit they can also survive periods of hunger. But, when they grow too quickly, their ability to survive is hampered, as studies by a research team at the Technical University of Munich (TUM) on E. coli bacteria show. ...

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New open source software predicts cell fate

05-Aug-2020

The study of cellular dynamics is crucial to understand how cells develop and how diseases progress. Scientist at Helmholtz Zentrum München and Technical University of Munich (TUM) created “scVelo” – a machine learning method and open source software to estimate the dynamics of gene activity in ...

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The tricks of the immune system

How the T-cell response changes in chronic virus infections

26-Jun-2020

More than half of the world's population is infected with the cytomegalovirus. The majority of people don't even notice the infection, since their immune systems keep the virus in check. Groups of T cells with a variety of virus-specific receptors play a key role in this process. Now researchers ...

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New x-ray method for Corona diagnosis ready for patient testing

Low-dose radiographs could reveal typical lung changes

12-May-2020

Researchers at the Technical University of Munich (TUM) have developed an innovative x-ray method for lung diagnostics, which they now plan to test in one of its first applications for diagnosis of the respiratory ailment Covid-19 caused by Coronavirus. The method could clearly identify ...

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