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He redefined cell biology by discovering signal peptides in proteins
20-Feb-2018 - Günter Blobel, a Nobel Prize-winning Rockefeller biologist who discovered the mechanisms by which proteins are targeted for delivery to specific locations within cells, died February 18 at 81. Blobel joined the Rockefeller faculty 51 years ago; he was the John D. Rockefeller Jr. Professor and had ...
01-Feb-2018 - A new method for monitoring interactions between cells, dubbed LIPSTIC by its creators, is much more than a cosmetic improvement over existing techniques. The breakthrough, led by The Rockefeller University assistant professor Gabriel Victora , offers scientists in a wide range of disciplines a ...
01-Aug-2017 - Some activity patterns in the brain can be dangerous, producing persistent dark moods that drain people's motivation, pleasure, and hope. For the past thirty years, pills like Prozac or Zoloft--collectively known as selective serotonin reuptake inhibitors, or SSRIs--have offered millions of ...
28-Feb-2017 - Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them. Researchers at The Rockefeller University have shed new light on a molecular pump that makes this possible, by determining ...
06-Feb-2017 - With the first detailed analysis of a cellular component from a close relative of the pathogen that causes tuberculosis, Rockefeller scientists are suggesting strategies for new drugs to curb this growing health problem. Each year, nearly half a million people around the world are infected with ...
30-Jan-2017 - Each cell in the body follows a strict protocol for manufacturing the proteins it needs to function. When a cell turns cancerous, however, its protein production goes off script. A new study led by researchers at The Rockefeller University takes a close look at one way in which this procedure ...
27-Jan-2017 - Without antiretroviral drug treatment, the majority of people infected with HIV ultimately develop AIDS, as the virus changes and evolves beyond the body's ability to control it. But a small group of infected individuals--called elite controllers--possess immune systems capable of defeating the ...
25-Jan-2017 - Using a state-of-the-art imaging technology in which molecules are deep frozen, scientists in Roderick MacKinnon 's lab at Rockefeller University have reconstructed in unprecedented detail the three-dimensional architecture of three channels that provide a path for specific types of ions to ...
06-Dec-2016 - Rockefeller scientists have created the first three-dimensional map of the protein responsible for cystic fibrosis, an inherited disease for which there is no cure. This achievemen offers the kinds of insights essential to better understanding and treating this often-fatal disease, which clogs ...
15-Jun-2016 - Biologically speaking, we carry the outside world within us. The food we ingest each day and the trillions of microbes that inhabit our guts pose a constant risk of infection--and all that separates us from these foreign entities is a delicate boundary made of a single layer of cells. The immune ...
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