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48 Current news of Rockefeller University

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Breast cancer cells turn killer immune cells into allies

16-Jul-2020

Researchers at Johns Hopkins University School of Medicine have discovered that breast cancer cells can alter the function of immune cells known as Natural killer (NK) cells so that instead of killing the cancer cells, they facilitate their spread to other parts of the body. The study, which will ...

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Intestinal inflammation: immune cells protect nerve cells after infection

New findings on the functions of the gut-brain axis

24-Jan-2020

In the event of an infection in the gastrointestinal tract, part of the tissue becomes inflamed, and intestinal nerve cells die off. Among other things, this loss in turn often leads to a restriction of the gastrointestinal motility, which is essential for a healthy digestion. In many cases, this ...

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Exploring genetic 'dark matter,' researchers gain new insights into autism and stroke

29-Jul-2019

With its elegant double helix and voluminous genetic script, DNA has become the of darling of nucleic acids. Yet, it is not all powerful. In order for DNA to realize its potential--for genes to become proteins--it must first be transcribed into RNA, a delicate molecule that requires intense care ...

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New method for studying gene expression could improve understanding of brain disease

29-Nov-2018

It takes a lot of cells to make a human brain. The organ houses not only an enormous quantity of neurons (tens of billions), but also an impressive diversity of neuron types. In recent years, scientists have been developing inventories of these cell classes--information that will be essential for ...

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Searching in soil, scientists find a new way to combat tuberculosis

05-Nov-2018

For decades, doctors have been using antibiotics to fight tuberculosis (TB). And consistently, the microbe responsible for the disease, Mycobacterium tuberculosis, has been fighting back. When confronted with current drugs, such as the antibiotic rifamycin, the bacterium often mutates in ways ...

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Study of protein 'trafficker' provides insight into autism and other brain disorders

25-Sep-2018

In the brain, as in business, connections are everything. To maintain cellular associates, the outer surface of a neuron, its membrane, must express particular proteins - proverbial hands that reach out and greet nearby cells. And, like a creepily long handshake, surface molecules can overstay ...

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Researchers uncover molecular mechanisms of rare skin disease

03-Aug-2018

Keratinocyte skin cells are common targets of the beta subtype of human papilloma virus. This usually harmless infection causes skin disease in people with rare gene mutations. You're probably infected with one or more subtypes of the human papilloma virus--and, as alarming as that may sound, ...

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Nobel laureate Günter Blobel dies at age 81

He redefined cell biology by discovering signal peptides in proteins

20-Feb-2018

Günter Blobel, a Nobel Prize-winning Rockefeller biologist who discovered the mechanisms by which proteins are targeted for delivery to specific locations within cells, died February 18 at 81. Blobel joined the Rockefeller faculty 51 years ago; he was the John D. Rockefeller Jr. Professor and had ...

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New tool for tracking 'kiss-and-run' communication between cells

01-Feb-2018

A new method for monitoring interactions between cells, dubbed LIPSTIC by its creators, is much more than a cosmetic improvement over existing techniques. The breakthrough, led by The Rockefeller University assistant professor Gabriel Victora , offers scientists in a wide range of disciplines a ...

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Faster-acting antidepressants may finally be within reach

01-Aug-2017

Some activity patterns in the brain can be dangerous, producing persistent dark moods that drain people's motivation, pleasure, and hope. For the past thirty years, pills like Prozac or Zoloft--collectively known as selective serotonin reuptake inhibitors, or SSRIs--have offered millions of ...

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