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26 Current news of Osaka University
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Biomarker helps identify 'window of opportunity' for cancer chemotherapy timing
11-Apr-2018
Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study describes a vascular stabilization biomarker that can visualize blood vessel activity, thus optimizing the timing of anticancer therapies including anti-angiogenics. Combination therapy using angiogenesis ...
Growing organs a few ink drops at a time
03-Jan-2018
Printed replacement human body parts might seem like science fiction, but this technology is rapidly becoming a reality with the potential to greatly contribute to regenerative medicine. Before any real applications, "bioprinting" still faces many technical challenges. Processing the bio-ink and ...
A new twist on asymmetric catalysis
28-Sep-2017
In the same way a glove will only fit one hand, molecules have the symmetry that controls their behavior and interactions. In drug design, this means reversing the symmetry of a molecule can mean the difference between an effective treatment or a compound that has serious negative effects. As a ...
The fork in the road to DNA repair
13-Jul-2017
The human body consists of trillions of cells, and within each are billions of DNA molecules. Strict maintenance of the molecules is essential to maintain a healthy cell and thus a healthy body. This maintenance is challenged by the daily bombardment of chemicals, UV light, radical oxgen and ...
How different drugs interact with the same target
18-May-2017
Tumor necrosis factor (TNF) is involved in a range of inflammatory diseases including rheumatoid and psoriatic arthritis, ankylosing spondylitis, and psoriasis. Several drugs that target TNF are available to treat these conditions; however, despite acting on the same target, their clinical ...
Computer simulation of protein synthesis reveals high complexity of cell machinery
20-Mar-2017
Life depends on proteins. These molecules are produced continually in our cells, which act as microscopic production lines - but the process is so complex we have barely begun to understand it. Exploring protein synthesis may, however, be the key to revealing how the body controls the thousands ...
Role of protein in pancreatic secretion suggests potential method for treating diabetes
12-Dec-2016
Research reveals opposing roles for SNAP23 protein in the enzyme- and hormone-secretion functions of the pancreas; SNAP23 inhibitor increased insulin secretion in mice, suggesting potential use as a novel therapy for diabetes Osaka, Japan - Movement of secretory molecules, such as hormones and ...
Behavior of sugar transport proteins visualized
18-Nov-2016
A group of researchers led by Kazuya Kikuchi, professor at the Graduate School of Engineering, Osaka University, clarified the role of a N-glycan chain on glucose transporter type 4 (GLUT4) by developing a method for visualizing intracellular trafficking of proteins. The GLUT4 translocation ...
May repairs full of mistakes develop into cancer?
25-May-2016
A group of researchers at Osaka University found that if DNA damage response (DDR) does not work when DNA is damaged by radiation, proteins which should be removed remain instead, and a loss of genetic information can be incited, which, when repaired incorrectly, will lead to the tumor ...
New method for exhaustively isolating olfactory receptors responding to specific odorants
29-Apr-2016
A research group led by Osaka University and Panasonic Corporation developed a method for making a prompt, exhaustive isolation of olfactory receptors (ORs) responding to the odorant of interest. This achievement will enable quick and easy exhaustive analysis of ORs responding to specific ...
