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The hidden machinery of a photosynthetic giant revealed

Rresearchers solved the structure of monomeric photosystem I by cryo-electron microscopy

22-Mar-2021

Photosynthesis is the fundament of almost all live on earth, and yet it is not understood down to the last detail. An international research team has now unravelled one of its secrets. The researchers from Ruhr-Universität Bochum (RUB), Osaka University, Japan, and Kafrelsheikh University, Egypt, ...

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Nanodiamonds feel the heat

Nanodiamond sensor can act as both heat sources and thermometers, and may lead to a new set of heat-based treatments for killing bacteria or cancer cells

19-Jan-2021

A team of scientists from Osaka University, The University of Queensland, and the National University of Singapore's Faculty of Engineering used tiny nanodiamonds coated with a heat-releasing polymer to probe the thermal properties of cells. When irradiated with light from a laser, the sensors ...

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Sorting out viruses with machine learning

Scientists develop a label-free method for identifying respiratory viruses which may lead to new rapid COVID-19 tests

19-Nov-2020

The ongoing global pandemic has created an urgent need for rapid tests that can diagnose the presence of the SARS-CoV-2 virus, the pathogen that causes COVID-19, and distinguish it from other respiratory viruses. Now, researchers from Japan have demonstrated a new system for single-virion ...

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Biomarker helps identify 'window of opportunity' for cancer chemotherapy timing

11-Apr-2018

Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study describes a vascular stabilization biomarker that can visualize blood vessel activity, thus optimizing the timing of anticancer therapies including anti-angiogenics. Combination therapy using angiogenesis ...

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Growing organs a few ink drops at a time

03-Jan-2018

Printed replacement human body parts might seem like science fiction, but this technology is rapidly becoming a reality with the potential to greatly contribute to regenerative medicine. Before any real applications, "bioprinting" still faces many technical challenges. Processing the bio-ink and ...

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A new twist on asymmetric catalysis

28-Sep-2017

In the same way a glove will only fit one hand, molecules have the symmetry that controls their behavior and interactions. In drug design, this means reversing the symmetry of a molecule can mean the difference between an effective treatment or a compound that has serious negative effects. As a ...

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The fork in the road to DNA repair

13-Jul-2017

The human body consists of trillions of cells, and within each are billions of DNA molecules. Strict maintenance of the molecules is essential to maintain a healthy cell and thus a healthy body. This maintenance is challenged by the daily bombardment of chemicals, UV light, radical oxgen and ...

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How different drugs interact with the same target

18-May-2017

Tumor necrosis factor (TNF) is involved in a range of inflammatory diseases including rheumatoid and psoriatic arthritis, ankylosing spondylitis, and psoriasis. Several drugs that target TNF are available to treat these conditions; however, despite acting on the same target, their clinical ...

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Computer simulation of protein synthesis reveals high complexity of cell machinery

20-Mar-2017

Life depends on proteins. These molecules are produced continually in our cells, which act as microscopic production lines - but the process is so complex we have barely begun to understand it. Exploring protein synthesis may, however, be the key to revealing how the body controls the thousands ...

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Role of protein in pancreatic secretion suggests potential method for treating diabetes

12-Dec-2016

Research reveals opposing roles for SNAP23 protein in the enzyme- and hormone-secretion functions of the pancreas; SNAP23 inhibitor increased insulin secretion in mice, suggesting potential use as a novel therapy for diabetes Osaka, Japan - Movement of secretory molecules, such as hormones and ...

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