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Protein hitch hiking into the cancer cell: the next generation of platinum drugs

The young spin-off "P4 Therapeutics" was awarded with the "Der Brutkasten Media Award"

02-Jul-2019

An interdisciplinary team of the University of Vienna and the Medical University of Vienna has developed a new platinum compound with great potential as anticancer drug. Based on a new strategy, scientists around Christian Kowol from the Department of Inorganic Chemistry, University of Vienna and ...

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Previously unknown bacterial strain identified

10-May-2019

Experts from MedUni Vienna/Vienna General Hospital have identified a previously unknown bacterial strain of the genus Leptospira. Infection with this bacterium triggered unusual neurological symptoms, reminiscent of myasthenia gravis, an autoimmune disease in which signal transmission is ...

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The lungs never forget

Specialised T-cells remember allergens

09-May-2019

According to a current study of the Medical University Vienna, specialised T memory lymphocytes in the lungs that react to inhaled allergens, cause attacks of allergic asthma. These T-helper 2-tissue resident memory cells, which are located in the lungs for a lifetime are known as Th2-TRMs, and ...

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From metabolite profiles to molecular biomarkers for colorectal cancer

16-Apr-2019

The aim of a European project (TRANSCAN) is to identify metabolite signatures that are associated with all stages in the development of colorectal cancer. Metabolomic analysis was performed on more than 2,000 plasma samples from individuals with colorectal cancer, colorectal adenoma and a control ...

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New hope for seasonal allergy sufferers

08-Mar-2019

One in three people is plagued by an allergy, triggered by foodstuffs, fungi, house dust mites or on a seasonal basis due to pollen. The latter group is the largest: around 800 million people worldwide suffer from some form of allergy to pollen, with the usual symptoms such as a runny nose, ...

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When changing one atom makes molecules better

A method to replace hydrogen with fluorine in organic molecules makes drugs more effective

07-Mar-2019

The development and improvement of pharmaceuticals plays the central role in the ongoing battle against human disease. Organic synthesis is the field that enables these developments as it offers the toolbox to diversify chemical structures. The group of Nuno Maulide, recently named the Scientist ...

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A needle-prick to protect against insect bites

05-Mar-2019

In persons with a severe allergy to bee or wasp venom, the bite of just one insect can even be fatal when it triggers acute respiratory distress and circulatory failure. A project funded by the FWF is working on vaccines that contain components of the insect venom in an attenuated form with ...

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Heavy Metals Weigh on Unborn Babies’ Health

Researchers explain workings of placental transport systems: spotlight on mercury and iron

22-Feb-2019

The toxic heavy metal mercury can find its way into the blood of unborn babies through the placenta by “camouflaging” itself as an amino acid. This finding was the outcome of research carried out by a team from Karl Landsteiner University of Health Sciences and the Medical University of Vienna ...

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Malignant pleural mesothelioma: new mechanism of spread discovered

17-Dec-2018

Malignant pleural mesothelioma is divided into three subtypes, one of which is particularly aggressive. Researchers from the Comprehensive Cancer Center (CCC) of MedUni Vienna and Vienna General Hospital have now managed to discover a mechanism that contributes to this aggressive behaviour: the ...

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Epigenetic analysis of aggressive brain tumors

30-Aug-2018

Glioblastoma is a brain cancer with devastating prognosis. A new collaborative study by scientists from CeMM, MedUni Vienna and the Austrian Brain Tumor Registry network demonstrates how epigenetic analysis of tumor samples collected in routine clinical practice could be used to better classify ...

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