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27-Feb-2018 - Laser physicists from the Laboratory of Attosecond Physics at the Ludwig-Maximilians-Universität and the Max Planck Institute of Quantum Optics have developed an extremely powerful broadband infrared light source. This light source opens up a whole new range of opportunities in medicine, life ...
Quality control in the mitochondria
01-Nov-2017 - A common feature of neurodegenerative diseases such as Alzheimer's, Parkinson's or Huntington's disease are deposits of aggregated proteins in the patient's cells that cause damage to cellular functions. Scientists report that, even in normal cells, aberrant aggregation-prone proteins are ...
14-Sep-2017 - The presence of DNA in mammalian cell cytoplasm triggers an immune response by binding to a dimeric enzyme, which inserts between DNA double helices to form the “rungs” of a ladder-like structure, as an LMU team has now shown. In higher organisms, the genetic material is normally confined to the ...
05-May-2017 - Competition within mixed bacterial populations can give rise to complex growth dynamics. Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich are probing the interplay between differential growth rates and stochastic factors in determining the composition of such populations. How do ...
Immune cells of the brain become active years before the disease becomes apparent
19-Dec-2016 - Little is known about the role of the brain‘s immune system in Alzheimer's disease. Researchers at the Munich site of the German Center for Neurodegenerative Diseases (DZNE) and the hospital of the Ludwig Maximilian University (LMU) Munich have now found an early immune response in individuals ...
RNA-based gene regulation with dynamic proteins
07-Nov-2016 - Before RNA transcripts of genes can program the synthesis of proteins, the non-coding regions are removed by the spliceosome, a complex molecular machine. The correct regulation of the splicing plays a central role for many cellular processes. By means of nuclear magnetic resonance measurements ...
28-Oct-2016 - LMU researchers have demonstrated how deregulation of an epigenetic mechanism that is active only in the early phases of neurogenesis triggers the subsequent death of neural cells. The generation of neurons from stem and progenitor cells is a complex, tightly regulated process known as ...
04-Oct-2016 - Light, when strongly concentrated, is enormously powerful. Now, a team of physicists led by Professor Jörg Schreiber from the Institute of Experimental Physics – Medical Physics, which is part of the Munich-Centre for Advanced Photonics (MAP), a Cluster of Excellence at LMU Munich, has used this ...
05-Sep-2016 - Blue-green algae may look simple, but their photosynthetic apparatus certainly isn’t. Its mode of assembly remains puzzling, but the loss of a small protein, variants of which are found in higher plants, clearly causes a lot to go wrong. Green plants are not the only organisms that possess the ...
05-Aug-2016 - Since the start of the HIV epidemic, there have been speculations as to why HIV and the immunodeficiency syndrome it causes have spread so much more in Africa than in other countries around the world. Scientists from the German Center for Infection Research (DZIF) have now, for the first time, ...
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