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Tiny “blinkers” reveal molecules inside cells

18-Mar-2019

LMU physicists led by Ralf Jungmann introduce an entirely new approach to super-resolution microscopy: Tiny ‘blinkers’ enable simultaneous imaging of multiple biomolecules. In everyday life, blinking lights can send signals – for example, that a car is going to turn. Now, researchers have ...

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Defective immune cells in the brain cause Alzheimer’s disease

Scientists are studying the role of immune cell activation in Alzheimer's disease

09-Jan-2019

Mutations of the TREM2 gene can significantly increase the risk of Alzheimer's disease. Scientists from the German Center for Neurodegenerative Diseases (DZNE) and the Ludwig-Maximilians-University Munich now shed light on the reasons why TREM2 is so important for brain health. They show that ...

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Imaging nerve-cell interactions

04-Jan-2019

A new imaging technique developed by LMU researchers is garnering lots of attention. Based on a method for making tissues, organs and even whole organisms transparent, it promises to transform studies of the nervous system in particular. A new bioimaging technology provides unprecedented insights ...

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The roles of RNA-RNA interactions

Chronic regeneration of damaged endothelial cells promotes the development of atherosclerosis

23-Jul-2018

Atherosclerosis – the condition popularly known as hardening of the arteries – develops almost exclusively at junctions and sharp turns in the arterial tree. This is because, at such sites, the endothelial cells that form the lining of the blood vessels are particularly sensitive to damage – and ...

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The biological role of europium

14-Jun-2018

Rare earth elements (REEs) are an indispensable component of the digital technologies that are now an integral part of our everyday life. Yet their biological role has been discovered only recently. A few years ago it became apparent that these metals are essential elements for methano- and ...

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DNA mimic outwits viral enzyme

Biomimetic chemistry

04-Apr-2018

Not only can synthetic molecules mimic the structures of their biological models, they can also take on their functions and may even successfully compete with them, as an artificial DNA sequence designed by LMU chemist Ivan Huc now shows. Chemist Ivan Huc finds the inspiration for his work in the ...

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Bacterial adhesion in vitro and in silico

How does a widespread bacterial pathogen adhere to tissues?

03-Apr-2018

Bacterial pathogens have evolved highly effective strategies that enable them to adhere to target cells and niches in the tissues of their host organisms. As demonstrated, they even make use of relatively unfamiliar physical principles. In collaboration with scientists at the University of ...

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22 new genetic risk factors for stroke identified

15-Mar-2018

Researchers have analyzed genetic data from half a million subjects in a search to identify the underlying causes of stroke, a complex vascular disease. Scientists at LMU led the the huge collaborative Project. Stroke is the second most common cause of both death and disability-adjusted ...

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A Keen Sense for Molecules

27-Feb-2018

Laser physicists from the Laboratory of Attosecond Physics at the Ludwig-Maximilians-Universität and the Max Planck Institute of Quantum Optics have developed an extremely powerful broadband infrared light source. This light source opens up a whole new range of opportunities in medicine, life ...

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Cellular power outage

Quality control in the mitochondria

01-Nov-2017

A common feature of neurodegenerative diseases such as Alzheimer's, Parkinson's or Huntington's disease are deposits of aggregated proteins in the patient's cells that cause damage to cellular functions. Scientists report that, even in normal cells, aberrant aggregation-prone proteins are ...

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