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19 Current news of Howard Hughes Medical Institute

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Expanding the optogenetics toolkit

22-Oct-2018

Controlling individual brain cells using light-sensitive proteins has proven to be a powerful tool for probing the brain's complexities. As this branch of neuroscience has expanded, so has the demand for a diverse palette of protein tools. A multidisciplinary team of 14 researchers from the ...

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DNA study casts light on century-old mystery of how cells divide

22-Jan-2018

Scientists have solved a longstanding puzzle of how cells are able to tightly package DNA to enable healthy cell division. Their findings shed light on how single cells can compact DNA 10,000-fold to partition it between two identical cells - a process that is essential for growth, repair and ...

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CRISPR treatment prevents hearing loss in mice

22-Dec-2017

Using molecular scissors wrapped in a greasy delivery package, researchers have disrupted a gene variant that leads to deafness in mice. A single treatment involving injection of a genome editing cocktail prevented progressive hearing loss in young animals that would have otherwise gone deaf, ...

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How the immune system identifies invading bacteria

17-Nov-2017

The body's homeland security unit is more thorough than any airport checkpoint. For the first time, scientists have witnessed a mouse immune system protein frisking a snippet of an invading bacterium. The inspection is far more extensive than researchers imagined: the immune system protein, ...

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Imaging techniques set new standard for super-resolution in live cells

31-Aug-2015

Scientists can now watch dynamic biological processes with unprecedented clarity in living cells using new imaging techniques developed by researchers at the Howard Hughes Medical Institute's Janelia Research Campus. The new methods dramatically improve on the spatial resolution provided by ...

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In the sea, a deadly form of leukemia is catching

13-Apr-2015

Outbreaks of leukemia that have devastated some populations of soft-shell clams along the east coast of North America for decades can be explained by the spread of cancerous tumor cells from one clam to another. Researchers call the discovery, reported in the Cell, "beyond surprising.""The ...

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New microscope collects dynamic images of the molecules that animate life

27-Oct-2014

Over the last decade, powerful new microscopes have dramatically sharpened biologists' focus on the molecules that animate and propel life. Now, a new imaging platform developed by Eric Betzig and colleagues at the Howard Hughes Medical Institute's Janelia Research Campus offers another leap ...

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New technique to sharpen microscope images

15-Apr-2014

The complexity of biology can befuddle even the most sophisticated light microscopes. Biological samples bend light in unpredictable ways, returning difficult-to-interpret information to the microscope and distorting the resulting image. New imaging technology developed at the Howard Hughes ...

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Newly discovered antibody recognizes many strains of flu virus

11-Aug-2011

Some vaccines are once-in-a-lifetime; others need a booster shot or two to maintain their potency. And then there's the flu vaccine, which only lasts a year. Strains of influenza virus change so much from year-to-year that new vaccines must be developed annually to target the strains of virus ...

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Evotec Establishes Research Collaboration With Harvard University and the Howard Hughes Medical Institute in Diabetes Research

Collaboration Established to Drive Innovation and Develop New Diabetes Therapies Targeting Beta Cell Regeneration

11-Mar-2011

Evotec AG announced the establishment of a research collaboration with Harvard University and the Howard Hughes Medical Institute (HHMI) aimed at discovering and developing new treatments in the field of diabetes.The initial goal of the collaboration is to pursue a comprehensive and systematic ...

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