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118 Current news of Harvard Universityrss
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Small engineering tweaks to botulinum toxin B could make it more effective and longer-lasting with fewer side effects
Botulinum toxins -- a.k.a. botox -- have a variety of uses in medicine: to treat muscle overactivity in overactive bladder, to correct misalignment of the eyes in strabismus, for neck spasms in cervical dystonia, and more. Two botulinum toxins, types A and B, are FDA-approved and widely used. ...
Magneto-Archimedes levitation for identification of illicit drugs in powdered mixtures
The composition of suspicious powders that may contain illicit drugs can be analyzed using a quick and simple method called magneto-Archimedes levitation (MagLev), according to a new study published in the journal Angewandte Chemie. A team of scientists at Harvard University, USA, has developed ...
Treatment increases healthspan in mice and could lead to increased longevity
As we age, our bodies tend to develop diseases like heart failure, kidney failure, diabetes, and obesity, and the presence of any one disease increases the risk of developing others. Traditional drug development targets only one condition per drug, largely ignoring the interconnectedness of ...
Programmable CRISPR-responsive smart materials could open the door to novel tissue engineering, bioelectronic, and diagnostic applications
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide position of the vast reaches of the genome. It is also being harnessed ...
Merck awarded a grant known as the Future Insight Prize for the first time
Merck awarded a grant known as the Future Insight Prize for the first time. Pardis Sabeti, Harvard University and the Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA, and James Crowe, Vanderbilt University Medical Center, Nashville, Tennessee, USA, were recognized for their ...
The human microbiome, the vast collection of microbes that colonize the surfaces lining many of our organs and our skin - is a critical pillar sustaining our general health. At any one time, 500 to 1,000 different species of bacteria inhabit us, which together contain far more genes than our ...
3D bioprinted, vascularized proximal tubules mimic the human kidney's reabsorption functions
Every day our kidneys tackle the daunting task of continuously cleaning our blood to prevent waste, salt and excess fluid from building up inside our bodies. To achieve this, the kidneys' approximately one million filtration units (glomeruli) first remove both waste products and precious ...
Examining a compound damaging DNA to understand its connection to cancer
For more than a decade, scientists have worked to understand the connection between colibactin, a compound produced by certain strains of E. coli, and colorectal cancer, but have been hampered by their inability to isolate the compound. So Emily Balskus instead decided to focus on the mess it ...
Deactivated platelets offer a potential drug-free, reversible antiplatelet therapy
Heart disease, stroke, sepsis, and cancer collectively cause the greatest number of deaths worldwide. They also have something else in common: all of them are associated with activated platelets, the cells that circulate in our bloodstreams and normally help form blood clots to stop bleeding and ...
Finding caps more than a decade of research on 'Hippo' pathway
It's known that cancer involves unchecked cell growth and that a biological pathway that regulates organ size, known at the Hippo pathway, is also involved in cancer. It's further known that a major player in this pathway, YAP, drives many types of tumors. Now, researchers at Boston Children's ...