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Brain stimulation against stress disorders?

One day it may be possible to cure brain disorders quite literally in our sleep – without taking pills


ETH researchers are using brain stimulation to investigate the consequences of stress and to find new therapies for treating stress-related psychiatric diseases. One day it may even be possible to cure brain disorders quite literally in our sleep – without taking pills. Some videos on the ...


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Making systems robust: Artificial genetic regulatory network introduced into living cell for the first time

Improving biotech and therapies


Both nature and technology rely on integral feedback mechanisms to ensure that systems resist external perturbations. ETH researchers have now used synthetic biology to design a new mechanism of this sort from scratch. For the first time, they have introduced it into a living cell as an ...


Redundancies in T cells


Researchers at ETH Zurich have discovered redundancies in the biochemical signalling pathways of immune cells. This finding has important implications for advances in cancer immunotherapy, among other areas. Oncologists have had great success with cancer immunotherapy in recent years, especially ...


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Breaking down pathological protein aggregates


ETH researchers have discovered a new mechanism that brain cells use to protect themselves from protein aggregates. Such aggregates play a key role in Parkinson’s and other neurodegenerative diseases. This new finding might provide the basis for new therapeutic approaches. Aggregates of the ...


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Early in vitro testing for adverse effects on embryos


ETH researchers have combined embryonic cells and liver cells in a new cell culture test. This combination lets them detect adverse effects that new medications may have on embryos early on in the drug development process. Medications have to be safe for mothers-to-be and for their unborn ...


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Fleming’s method in miniature


Scientists in the Department of Biosystems Science and Engineering at ETH Zurich in Basel have developed a method with which they can quickly test a very large number of molecules for antibiotic effect. With it, they have already successfully discovered new antibiotic candidates produced by ...


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Bacteria reveal strong individuality when navigating a maze


Researchers from ETH Zurich demonstrate that genetically identical cells exhibit differing responses in their motility towards chemical attractants. Average values hide the full picture when it comes to describing the behaviour of bacteria. Although they are considered the simplest of all life ...


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A biosynthetic dual-core cell computer


ETH researchers have integrated two CRISPR-Cas9-based core processors into human cells. This represents a huge step towards creating powerful biocomputers. Controlling gene expression through gene switches based on a model borrowed from the digital world has long been one of the primary ...


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First bacterial genome created entirely with a computer

The method has the potential to revolutionise biotechnology


Scientists at ETH Zurich have developed a new method that greatly simplifies the production of large DNA molecules containing many hundreds of genes. With this method, they have built the first genome of a bacterium entirely designed by a computer algorithm. The method has the potential to ...


Major step towards individual cancer immunotherapy

ETH spin-off founded for commercial further development of technique


Medicine has great hopes for personalised cancer immunotherapy. The idea is to have a vaccine prompt the immune system to fight a tumour. Scientists at ETH Zurich have developed a method that allows them to determine which molecules are suited to patient-specific immunisation. Cells belonging to ...


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