Potential New Treatment for Heart Attack

Prospective drug found by testing in human heart muscle grown from stem cells

11-Mar-2019 - Domainex announced that a team of its scientists, working in close partnership with Professor Michael Schneider and his team at Imperial College, have found a potential new drug candidate for treating the heart damage caused during a heart attack by targeting the way the heart reacts to stress, ...

Domainex appoints Dr Trevor Perrior as Chief Executive Officer

24-Sep-2018 - Domainex Ltd announced the appointment of Dr Trevor Perrior as Chief Executive Officer, effective from 1stOctober 2018. Dr Perrior has held the position of Director of Research and Chief Scientific Officer at Domainex since 2005. The company has grown significantly during his tenure, delivering ...

Domainex appoints Timo Veromaa as Executive Chairman

03-Apr-2017 - Domainex Ltd announces that Dr Timo Veromaa has been appointed Executive Chairman with immediate effect. His appointment expands and strengthens the existing Board and Executive Management Team; Dr Veromaa will have a pivotal role in leading the organisation through a continuing period of growth ...

Domainex Secures £1.4m Biomedical Catalyst Award

11-Jul-2014 - Domainex Ltd announced that its lead compound has demonstrated a more potent effect in a key model of chronic obstructive pulmonary disease (COPD) than either roflumulast or a p38 inhibitor. It has also successfully won a £1.4m Biomedical Catalyst Award to support further development towards ...

University of Warwick Wins Domainex’s First Discovery STAR Award

04-Sep-2013 - Domainex Ltd. has announced that the recipient of its first Discovery STAR Award; Professor Vilmos Fulop of the University of Warwick. This award will give Professor Fulop access to Domainex’s drug discovery capabilities to support his research for a much-needed new treatment for Chagas ...

Horizon Discovery and Domainex Ltd Collaborate to Support Lead Optimization Oncology Program

Horizon’s isogenic cell lines accurately modeling tumor mutations to be used to profile lead compounds

08-Aug-2012 - Horizon Discovery Ltd announced it has signed an agreement with Domainex to support Domainex’s TBK1/ IKKe oncology research and development program, which is conducted in collaboration with The Institute of Cancer Research, London. Under the terms of the agreement, Horizon will profile a number ...

UCB and Domainex Collaboration Provides Valuable Information on Cancer Drug Target

Combinatorial domain hunting technology aids identification of MEK protein suitable for structure-based drug discovery

13-Mar-2012 - UCB and Domainex Ltd have jointly published the results of a collaboration in the field of cancer drug discovery. Working together, the two companies have developed an experimental system to study the three-dimensional structure of Mitogen-activated protein kinase kinase (MAPKK, also known as ...

Domainex to Invest in its Drug Discovery Services and Internal Oncology Pipeline in 2011

09-Mar-2011 - Domainex Ltd has announced plans to significantly expand its medicinal chemistry and biology capabilities in 2011. The expansion will involve relocation to larger laboratories in Cambridge and investment in new technologies that will enhance its current service offering. This will allow Domainex ...

Domainex Wins Genesis Award for its Work in Supporting Translational Research

23-Dec-2010 - Domainex Ltd has won the 2010 Genesis Life Science Innovation and Enterprise Programme Of The Year Award. This Award was made in recognition of Domainex’s proactive work on promoting academic-industry collaborations, and was adjudicated by leading representatives of the biotechnology and ...

Domainex Collaborates with Sigma-Aldrich to Advance the Study of Epigenetic Proteins Involved in Cancer and Stem Cell Biology

17-Nov-2010 - Domainex Ltd announced a collaboration with Sigma-Aldrich that will provide essential tools, including biochemical assays and monoclonal antibodies, for the study of proteins involved in the rapidly developing field of epigenetics. These epigenetic proteins regulate DNA expression and can be ...