Coronavirus: Study finds further door opener into the cell

Researchers have identified neuropilin-1 as a factor that can facilitate SARS-CoV-2 entry into the cells’ interior

28-Oct-2020 - The coronavirus SARS-CoV-2 is known to infect cells via the receptor ACE2. An international research team under German-Finnish coordination has now identified neuropilin-1 as a factor that can facilitate SARS-CoV-2 entry into the cells’ interior. Neuropilin-1 is localized in the respiratory and ...

Highly effective antibodies against the coronavirus were identified

Berlin scientists lay basis for a passive vaccination

25-Sep-2020 - Researchers at the German Center for Neurodegenerative Diseases (DZNE) and Charité - Universitätsmedizin Berlin have identified highly effective antibodies against the coronavirus SARS-CoV-2 and are now pursuing the development of a passive vaccination. In this process, they have also discovered ...

Risk gene for Alzheimer’s has early effects on the brain

Results of a study in 82 young adults

21-Sep-2020 - A genetic predisposition to late-onset Alzheimer’s disease affects how the brains of young adults cope with certain memory tasks. Researchers from the German Center for Neurodegenerative Diseases (DZNE) and the Ruhr-Universität Bochum report on this in the scientific journal “Current Biology”. ...

COVID-19: Immune system on the wrong track

"Many indications suggest that the immune system stands in its own way during severe courses of COVID-19"

07-Aug-2020 - Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction – rather, the immune response is caught in a continuous loop of activation and inhibition. Experts from Charité – Universitätsmedizin Berlin, the University of Bonn, ...

Cleaning craze in the brain

Synaptic protein waste" was collected more quickly when the presynaptic protein bassoon is missing

28-May-2020 - Synapses consist of hundreds of different proteins. For correct transmission of brain signals, their building blocks must constantly be checked for functionality and replaced by new ones. A team of researchers from the Leibniz Institute of Neurobiology Magdeburg, the German Centre for ...

Immune cells against Alzheimer’s?

Researchers investigate new therapeutic approach

11-Mar-2020 - Scientists at the German Center for Neurodegenerative Diseases (DZNE), the Ludwig-Maximilians-Universität (LMU) Munich and Denali Therapeutics (South San Francisco, CA, USA)have developed an approach to stimulate immune cells of the brain in such a way that they might possibly provide better ...

Alzheimer’s disease: Protective immune response in the brain?

02-Sep-2019 - LMU researchers Christian Haass and Michael Ewers have identified a factor that might possibly delay the emergence and slow the progression of Alzheimer’s disease. Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the Institute for Stroke and Dementia Research (ISD) at ...

Researchers Identify Key Proteins for the Repair of Nerve Fibers

12-Aug-2019 - Scientists at the German Center for Neurodegenerative Diseases (DZNE) have identified a group of proteins that help to regenerate damaged nerve cells. It is commonly accepted that neurons of the central nervous system shut down their ability to grow when they no longer need it; this occurs ...

Parkinson’s: New Study Associates Oxidative Stress With the Spreading of Aberrant Proteins

18-Jul-2019 - Oxidative stress could be a driving force in the spreading of aberrant proteins involved in Parkinson’s disease. This is the result of lab studies by researchers of the German Center for Neurodegenerative Diseases (DZNE). Parkinson’s is a neurodegenerative disease with clinical manifestations ...

How fish brain cells react to Alzheimer’s disease

25-Apr-2019 - Zebrafish, in contrast to humans, have outstanding regenerative capacities: If brain cells are lost due to illness or injury, they will easily regrow from so-called progenitor cells. With sophisticated methods, researchers from the German Center for Neurodegenerative Diseases (DZNE) and the ...