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37 Current news of Deutsches Zentrum für Neurodegenerative Erkrankungenrss
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Zinc finger technology as a starting point for future therapies
Researchers at the DZNE (Germany), at Massachusetts General Hospital (USA) and at the genomic medicine company Sangamo Therapeutics, Inc. tested a novel gene regulation approach to treat brain diseases such as Alzheimer's in laboratory studies. It leverages zinc finger proteins, which ...
Drug Screening with 3D Cell Cultures
On the basis of a license agreement with the German Center for Neurodegenerative Diseases (DZNE) and the Leibniz Institute of Polymer Research Dresden (IPF), the Dresden-based start-up “Neuron-D GmbH” is developing a high-throughput system for testing drug candidates to treat neurodegenerative ...
Researchers have identified neuropilin-1 as a factor that can facilitate SARS-CoV-2 entry into the cells’ interior
The coronavirus SARS-CoV-2 is known to infect cells via the receptor ACE2. An international research team under German-Finnish coordination has now identified neuropilin-1 as a factor that can facilitate SARS-CoV-2 entry into the cells’ interior. Neuropilin-1 is localized in the respiratory and ...
Berlin scientists lay basis for a passive vaccination
Researchers at the German Center for Neurodegenerative Diseases (DZNE) and Charité - Universitätsmedizin Berlin have identified highly effective antibodies against the coronavirus SARS-CoV-2 and are now pursuing the development of a passive vaccination. In this process, they have also discovered ...
Results of a study in 82 young adults
A genetic predisposition to late-onset Alzheimer’s disease affects how the brains of young adults cope with certain memory tasks. Researchers from the German Center for Neurodegenerative Diseases (DZNE) and the Ruhr-Universität Bochum report on this in the scientific journal “Current Biology”. ...
"Many indications suggest that the immune system stands in its own way during severe courses of COVID-19"
Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction – rather, the immune response is caught in a continuous loop of activation and inhibition. Experts from Charité – Universitätsmedizin Berlin, the University of Bonn, ...
Synaptic protein waste" was collected more quickly when the presynaptic protein bassoon is missing
Synapses consist of hundreds of different proteins. For correct transmission of brain signals, their building blocks must constantly be checked for functionality and replaced by new ones. A team of researchers from the Leibniz Institute of Neurobiology Magdeburg, the German Centre for ...
Researchers investigate new therapeutic approach
Scientists at the German Center for Neurodegenerative Diseases (DZNE), the Ludwig-Maximilians-Universität (LMU) Munich and Denali Therapeutics (South San Francisco, CA, USA)have developed an approach to stimulate immune cells of the brain in such a way that they might possibly provide better ...
LMU researchers Christian Haass and Michael Ewers have identified a factor that might possibly delay the emergence and slow the progression of Alzheimer’s disease. Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the Institute for Stroke and Dementia Research (ISD) at ...
Scientists at the German Center for Neurodegenerative Diseases (DZNE) have identified a group of proteins that help to regenerate damaged nerve cells. It is commonly accepted that neurons of the central nervous system shut down their ability to grow when they no longer need it; this occurs ...