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47 Current news of Deutsches Krebsforschungszentrum

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Using mini colons to detect functional differences and weaknesses of colorectal cancer

Pooled in vitro and in vivo CRISPR-Cas9 screening identifies tumor suppressors in human colon organoids

07-May-2020

One of the main features of colorectal cancer is that there are considerable differences between the tumors of individual patients - at genetic level and hence in terms of the response to treatment too. Researchers from the German Cancer Consortium (DKTK) have developed a method that allows these ...

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Preventing metastasis - an antibody with therapeutic potential

New principle for slowing down the metastatic dissemination of cancer cells

04-May-2020

A receptor in the cell layer that lines the blood vessels from the inside stimulates both the formation of new blood vessels in tumors and metastasis. Scientists at the German Cancer Research Center in Heidelberg (DKFZ) and the Mannheim Medical Faculty of the University of Heidelberg have ...

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Remote medical image diagnosis

Startup provides app free of charge during corona crisis

06-Apr-2020

The current crises caused by the fast spread of covid-19 is forcing clinics and its medical staff to take actions that otherwise would require months or years: Home office and the provision of mobile software solutions. mbits, a spin-off of the German Cancer Research Center (DKFZ), has ...

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Unstable chromosomes can promote breast cancer

Altered chromosomes lead to treatment resistance

03-Mar-2020

If chromosomes are unevenly distributed or otherwise altered during cell division, this normally damages the daughter cells and impairs their viability. Not in cancer cells, however, in which chromosome instability can actually confer a growth advantage under certain circumstances. Moreover, as ...

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Using oxygen to make cancer visible

20-Feb-2020

Scientists from the German Cancer Research Center have developed a new method that uses oxygen to identify brain tumors more effectively by magnetic resonance tomography (MRT). To do so, they rely on a metabolic feature of the tumor cells that they can make visible using a completely new imaging ...

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Potential pivot for a more effective cancer immunotherapy

31-Jan-2020

Scientists from the Biomedical Research Foundation of the Academy of Athens (Greece), the Institute of Clinical Chemistry and Laboratory Medicine of the Carl Gustav Carus University Hospital Dresden and the National Center for Tumor Diseases Dresden (NCT/UCC), in collaboration with an ...

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How dying cells prevent dangerous immune reactions

14-Jan-2020

Dying cells in the body can keep the immune system in check, thus preventing unwanted immune responses against the body's own tissues. Scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now identified a receptor on immune cells that activates this ...

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Innovative method delivers new insights into the stem cell microenvironment – Bone marrow in 3D

02-Jan-2020

Researchers from the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Center (DKFZ) in Heidelberg, Germany, have developed new methods to reveal the three-dimensional organisation of bone marrow at a single cell level. Since bone marrow harbours blood stem cells ...

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Cell death or cancer growth: a question of cohesion

21-Nov-2019

Activation of CD95, a receptor found on all cancer cells, triggers programmed cell death – or does the opposite, namely stimulates cancer cell growth. Scientists from the German Cancer Research Center (DKFZ) have now shown that the impact of CD95 activation depends on whether there are isolated ...

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Intestinal bacteria could influence the development of multiple sclerosis

14-Nov-2019

A tryptophan-free diet in mice changes the composition of the intestinal bacteria and protects against symptoms of experimentally generated multiple sclerosis. Tryptophan is an essential amino acid, i.e. a protein component which cannot be produced by the body itself, but must be obtained from ...

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