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Two colour technique reveals how X-ray lasers damage biomolecules

Step to a fuller understanding of how X-ray flashes modify the structure of proteins

03-Jun-2020

X-ray lasers can reveal the spatial structures of biomolecules that are hard to come by with other methods. However, the intense X-ray flashes vaporise the samples almost immediately. An international team of scientists has now followed how this radiation damage spreads in biomolecules to ...

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Research team finds possible new approach for sleeping sickness drugs

X-ray laser reveals structure of a key enzyme of the parasite Trypanosoma brucei

04-Feb-2020

Using ultra-bright X-ray flashes, a team of researchers has tracked down a potential target for new drugs against sleeping sickness: The scientists have decoded the detailed spatial structure of a vital enzyme of the pathogen, the parasite Trypanosoma brucei. The result provides a possible ...

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Using corkscrew lasers to separate mirror molecules

Innovative approach could deepen insight into the mysterious handedness of life

13-Dec-2019

Many of the molecular building blocks of life have two versions that are mirror images of one another, known as enantiomers. Although seemingly identical, the two enantiomers can have completely different chemical behaviour – a fact that has major implications in our day-to-day lives. For ...

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First molecular movies at European XFEL

Researchers follow dynamics of light-sensitive protein with European X-ray laser

26-Nov-2019

An international team of researchers has made the first film of the dynamics of a biomolecule at the European X-ray laser European XFEL. In a paper published in Nature Methods, scientists show how to effectively use the high X-ray pulse repetition rate of the European X-ray laser European XFEL to ...

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How molecular footballs burst in an X-ray laser beam

Study shows effect of X-ray flashes on sensitive biomolecules

26-Sep-2019

An international research team has observed in real time how football molecules made of carbon atoms burst in the beam of an X-ray laser. The study shows the temporal course of the bursting process, which takes less than a trillionth of a second, and is important for the analysis of sensitive ...

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Breaking ground for the Innovation Centre on the DESY Campus

Incubator for high-tech start-ups is a first milestone on the way to Science City Bahrenfeld

17-Apr-2019

The mayor of Hamburg, Dr. Peter Tschentscher, symbolically broke the ground together with his deputy, the Senator for Science Katharina Fegebank, the Chairman of DESY’s Board of Directors, Dr. Helmut Dosch, the President of the University of Hamburg, Dr. Dieter Lenzen, and DESY’s Chief Technology ...

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For Start-ups and Founders: Inauguration of DESY Innovation Village

The new DESY Innovation Village is the place for start-ups and innovative projects at DESY

26-Feb-2019

“I Love Innovation” was the fitting motto with which the DESY Innovation Village was officially inaugurated on Valentine’s Day, in the presence of DESY’s Board of Directors and representatives of the federal and local Hamburg governments. It will offer DESY start-ups offices, workshops and ...

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X-ray experiments reveal important mechanism behind parkinsonian disorders

Gene defect in hereditary forms of the neurological disorder results in manganese poisoning inside cells

21-Jan-2019

A new X-ray study has revealed one of the key mechanisms behind certain familial-parkinsonian disorders. The study demonstrates in detail how poisoning with the metal manganese occurs inside a cell, leading to parkinsonian symptoms. It found that a specific genetic defect results in manganese ...

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A new path through the looking-glass

Innovative experimental scheme can create mirror molecules

14-Nov-2018

Exploring the mystery of the molecular handedness in nature, scientists have proposed a new experimental scheme to create custom-made mirror molecules for analysis. The technique can make ordinary molecules spin so fast that they lose their normal symmetry and shape and instead form mirrored ...

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New technique enables spatial separation of peptide structures

Milestone on the way to direct imaging of individual biomolecules

01-Nov-2018

A team of scientists at DESY and Universität Hamburg has reached another milestone towards the direct imaging of individual biomolecules: the group led by Jochen Küpper from the Center for Free-Electron Laser Science developed a new experimental technique which enables the separation of different ...

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