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Highly effective antibodies against the coronavirus were identified

Berlin scientists lay basis for a passive vaccination

25-Sep-2020

Researchers at the German Center for Neurodegenerative Diseases (DZNE) and Charité - Universitätsmedizin Berlin have identified highly effective antibodies against the coronavirus SARS-CoV-2 and are now pursuing the development of a passive vaccination. In this process, they have also discovered ...

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COVID-19: Immune system on the wrong track

"Many indications suggest that the immune system stands in its own way during severe courses of COVID-19"

07-Aug-2020

Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction – rather, the immune response is caught in a continuous loop of activation and inhibition. Experts from Charité – Universitätsmedizin Berlin, the University of Bonn, ...

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HIV-1: The undercover agent

The AIDS virus HIV-1 goes largely unnoticed by T-cells of the immune system thanks to an ingenious propagation strategy

30-Jul-2020

Antibodies are not the only protection against viruses: At a much earlier stage, infected cells detect components of a virus with the help of internal sensors and trigger an immune response. This is an element of what is known as innate immunity, and helps prevent viruses from spreading further. ...

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Could the blood of COVID-19 patients be used to predict disease progression?

Study discovers differences in the blood samples of severe and mild cases

09-Jun-2020

Researchers from Charité – Universitätsmedizin Berlin and the Francis Crick Institute have identified 27 proteins which are present at different levels in the blood of COVID-19 patients, depending on the severity of their symptoms. These biomarker profiles could be used to predict disease ...

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Cleaning craze in the brain

Synaptic protein waste" was collected more quickly when the presynaptic protein bassoon is missing

28-May-2020

Synapses consist of hundreds of different proteins. For correct transmission of brain signals, their building blocks must constantly be checked for functionality and replaced by new ones. A team of researchers from the Leibniz Institute of Neurobiology Magdeburg, the German Centre for ...

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Diagnostics, meet CRISPR

15-Apr-2020

A new diagnostic test to quickly and easily monitor kidney transplant patients for infection and rejection relies on a simple urine sample and a powerful partner: the gene-editing technology CRISPR. Michael Kaminski, who developed it, leads a new Emmy Noether Group at the MDC & Charité. The ...

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What cells does the novel coronavirus attack?

09-Apr-2020

Scientists from the Berlin Institute of Health (BIH), Charité – Universitätsmedizin Berlin and the Thorax Clinic at Heidelberg University Hospital, whose collaboration is taking place under the auspices of the German Center for Lung Research (DZL), have examined samples from non-virus infected ...

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Preventing spread of SARS coronavirus-2 in humans

Infection researchers identify potential drug

09-Mar-2020

Viruses must enter cells of the human body to cause disease. For this, they attach to suitable cells and inject their genetic information into these cells. Infection biologists from the German Primate Center - Leibniz Institute for Primate Research in Göttingen, together with colleagues at ...

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Cellular waste system disposes of coronavirus

Scientists discover a possible starting point for medications to treat coronavirus infections

11-Feb-2020

Research into basic cellular processes continually leads to unexpected discoveries. A study by researchers from the Max Planck Institute of Psychiatry in Munich, the University Clinic in Bonn, and Charité in Berlin illustrates how even basic research can lead to new medical treatments. The ...

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Recognise and control new variants of the deadly Ebola virus more quickly

11-Feb-2020

The situation is extraordinary: there have only ever been four declarations of public health emergencies of international concern in the past and now there are two at the same time. Whilst the risks associated with the novel coronavirus are still unclear, people in the Democratic Republic of the ...

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