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Could the blood of COVID-19 patients be used to predict disease progression?

Study discovers differences in the blood samples of severe and mild cases

09-Jun-2020

Researchers from Charité – Universitätsmedizin Berlin and the Francis Crick Institute have identified 27 proteins which are present at different levels in the blood of COVID-19 patients, depending on the severity of their symptoms. These biomarker profiles could be used to predict disease ...

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Cleaning craze in the brain

Synaptic protein waste" was collected more quickly when the presynaptic protein bassoon is missing

28-May-2020

Synapses consist of hundreds of different proteins. For correct transmission of brain signals, their building blocks must constantly be checked for functionality and replaced by new ones. A team of researchers from the Leibniz Institute of Neurobiology Magdeburg, the German Centre for ...

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Diagnostics, meet CRISPR

15-Apr-2020

A new diagnostic test to quickly and easily monitor kidney transplant patients for infection and rejection relies on a simple urine sample and a powerful partner: the gene-editing technology CRISPR. Michael Kaminski, who developed it, leads a new Emmy Noether Group at the MDC & Charité. The ...

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What cells does the novel coronavirus attack?

09-Apr-2020

Scientists from the Berlin Institute of Health (BIH), Charité – Universitätsmedizin Berlin and the Thorax Clinic at Heidelberg University Hospital, whose collaboration is taking place under the auspices of the German Center for Lung Research (DZL), have examined samples from non-virus infected ...

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Preventing spread of SARS coronavirus-2 in humans

Infection researchers identify potential drug

09-Mar-2020

Viruses must enter cells of the human body to cause disease. For this, they attach to suitable cells and inject their genetic information into these cells. Infection biologists from the German Primate Center - Leibniz Institute for Primate Research in Göttingen, together with colleagues at ...

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Cellular waste system disposes of coronavirus

Scientists discover a possible starting point for medications to treat coronavirus infections

11-Feb-2020

Research into basic cellular processes continually leads to unexpected discoveries. A study by researchers from the Max Planck Institute of Psychiatry in Munich, the University Clinic in Bonn, and Charité in Berlin illustrates how even basic research can lead to new medical treatments. The ...

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Recognise and control new variants of the deadly Ebola virus more quickly

11-Feb-2020

The situation is extraordinary: there have only ever been four declarations of public health emergencies of international concern in the past and now there are two at the same time. Whilst the risks associated with the novel coronavirus are still unclear, people in the Democratic Republic of the ...

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A new treatment strategy against MERS

Licensed drugs effective in cells

31-Jan-2020

First identified in 2012, the MERS-coronavirus is capable of causing severe and often fatal pneumonia. There are no effective treatments for MERS. Researchers from the German Center for Infection Research (DZIF) at Charité – Universitätsmedizin Berlin recently identified a cellular recycling ...

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Researchers develop first diagnostic test for novel coronavirus in China

17-Jan-2020

Researchers from the German Center for Infection Research (DZIF) at Charité - Universitätsmedizin Berlin have developed a new laboratory assay to detect the novel Chinese coronavirus. The assay protocol has now been published by WHO as a guideline for diagnostic detection. The new assay enables ...

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DNA saturation mutagenesis: Identifying which mutations really cause disease

15-Aug-2019

Scientists at the Berlin Institute of Health (BIH) and Charité – Universitätsmedizin Berlin, working with colleagues from the United States, have selectively modified the control regions of 20 disease-relevant genes. This enabled them to identify precisely those modifications that have the ...

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