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Lights on for Germ-Free Wound Dressings

Biomimetic hydrogel with photodynamic antimicrobial effect

21-Jan-2020

Infections are a dreaded threat that can have fatal consequences after an operation, in the treatment of wounds, and during tissue engineering. Biomimetic hydrogels with “built-in” antimicrobial properties can significantly decrease this danger. In the journal Angewandte Chemie, scientists have ...

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Sensing Protein Wellbeing

Molecular probe maps misfolded proteome state in live cells

13-Jan-2020

The folding state of the proteins in live cells often reflect the cell’s general health. Australian scientists have developed a molecular probe that senses the state of the proteome—the entire set of the proteins—by measuring the polarity of the protein environment. The fluorescence signal of the ...

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Separating Drugs with MagLev

Magneto-Archimedes levitation for identification of illicit drugs in powdered mixtures

11-Dec-2019

The composition of suspicious powders that may contain illicit drugs can be analyzed using a quick and simple method called magneto-Archimedes levitation (MagLev), according to a new study published in the journal Angewandte Chemie. A team of scientists at Harvard University, USA, has developed ...

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Immune System Upgrade: nanoparticles act as artificial enzymes

Catalytic immunotherapy for cancer

30-Oct-2019

Theoretically, our immune system could detect and kill cancer cells. Unfortunately, tumors are well armed to fight these attacks. Despite modern cancer treatments, metastases and relapses remain a major problem. Increasing anti-tumor immunity might now be made possible, thanks to copper telluride ...

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Little Heaps of Silver, All Wrapped Up

Determination of the crystal structure of a DNA-stabilized silver nanocluster

13-Sep-2019

Nanoclusters are little “heaps” of a few atoms that often have interesting optical properties and could become useful probes for imaging processes in areas such as biomedicine and diagnostics. In the journal Angewandte Chemie, researchers have introduced a nanocluster of 16 silver atoms ...

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Analysis and Detoxification in One Step

A smart chemoenzymatic method detects and removes hazardous phenols

13-Aug-2019

Many industrial and agriculture processes use chemicals that can be harmful for workers and the ecosystems where they accumulate. Researchers from Thailand have now developed a bioinspired method to detect and detoxify these chemicals in only one step. As they report in the journal Angewandte ...

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Direct detection of circulating tumor cells in blood samples

Enhanced Glow

09-Aug-2019

Tumor cells circulating in blood are markers for the early detection and prognosis of cancer. However, detection of these cells is challenging because of their scarcity. In the journal Angewandte Chemie, scientists have now introduced an ultrasensitive method for the direct detection of ...

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Actively Swimming Gold Nanoparticles

Chemotactic movement on the macroscale by a swarm of bacteria-mimicking nanoswimmers

07-Aug-2019

Bacteria can actively move towards a nutrient source—a phenomenon known as chemotaxis—and they can move collectively in a process known as swarming. Chinese scientists have redesigned collective chemotaxis by creating artificial model nanoswimmers from chemically and biochemically modified gold ...

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The Art of Sensing within the Skin

Dermal tattoo sensors for the detection of blood pH change and metabolite levels

22-Jul-2019

The art of tattooing may have found a diagnostic twist. A team of scientists in Germany have developed permanent dermal sensors that can be applied as artistic tattoos. As detailed in the journal Angewandte Chemie, a colorimetric analytic formulation was injected into the skin instead of tattoo ...

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Imprinted Spheres Fight Breast Cancer

Inhibition of HER2 on tumor cells by molecularly imprinted nanoparticles

05-Jul-2019

A particularly aggressive, metastasizing form of cancer, HER2-positive breast cancer, may be treated with nanoscopic particles “imprinted” with specific binding sites for the receptor molecule HER2. As reported by Chinese researchers in the journal Angewandte Chemie, the selective binding of the ...

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