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Biotage acquires ATDBio

Biotage strengthens its position in DNA and RNA Oligonucleotide synthesis and purification


Biotage AB has entered into an agreement to acquire all outstanding shares in the privately held company ATDBio Limited based in Oxford and Southampton, UK, for a total purchase price of approx. 45 MGBP on a debt free and cash free basis (corresponding to approx. 534.4 MSEK) financed through a ...


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Nobel Prize in Chemistry 2021 for the development of asymmetric organocatalysis

An ingenious tool for building molecules


The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry 2021 to Benjamin List, Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany and David W.C. MacMillan, Princeton University, USA “for the development of asymmetric organocatalysis”. Building ...


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Nobel Prize in Physiology or Medicine 2021 awarded to US scientists David Julius and Ardem Patapoutian

How do we perceive the world?


The Nobel Assembly at Karolinska Institutet has decided to award the 2021 Nobel Prize in Physiology or Medicine jointly to David Julius and Ardem Patapoutian for their discoveries of receptors for temperature and touch. Our ability to sense heat, cold and touch is essential for survival and ...


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Cavalier King Charles spaniels carry more harmful genetic variants than other breeds

Genomic study also identified genetic variants linked to a common heart condition in the breed


Recent dog breeding practices have loaded up cavalier King Charles spaniels with disease-causing mutations, including variants linked to the common heart condition, myxomatous mitral valve disease (MMVD). Erik Axelsson of Uppsala University and colleagues published these new findings September ...


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Graphene binds drugs which kill bacteria on medical implants

Simple method paves way for future drugs


Bacterial infections relating to medical implants place a huge burden on healthcare and cause great suffering to patients worldwide. Now, researchers at Chalmers University of Technology, Sweden, have developed a new method to prevent such infections, by covering a graphene-based material with ...


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How chemicals in plastic may cause lower IQ levels

The effects of environmental chemicals at the molecular level


The chemical bisphenol F (found in plastics) can induce changes in a gene that is vital for neurological development. This discovery was made by researchers at the universities of Uppsala and Karlstad, Sweden. The mechanism could explain why exposure to this chemical during the fetal stage may be ...


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Unique AI method for generating proteins will speed up drug development

From computer design to working proteins in just a few weeks


Artificial Intelligence is now capable of generating novel, functionally active proteins, thanks to recently published work by researchers from Chalmers University of Technology, Sweden. "What we are now able to demonstrate offers fantastic potential for a number of future applications, such as ...


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Inhibitor in a Tunnel

New method for the development of choline acetyltransferase inhibitors


The enzyme choline acetyltransferase (ChAT) catalyzes the synthesis of the neurotransmitter acetylcholine and could be a target molecule for pharmaceuticals. A Swedish research team has now determined the mechanism by which arylvinylpyridinium (AVP), a known class of ChAT inhibitors, functions. ...


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New tests identify very early changes in Alzheimer's disease before symptoms appear


Researchers at the University of Gothenburg in Sweden, together with their colleagues at the Barcelona Beta Research Centre in Spain, the University Medical Centre in Ljubljana, Slovenia, and the University of Paris, have found new forms of tau protein that become abnormal in the very early ...


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Cell ageing can be slowed by oxidants

Less food gives longer life


At high concentrations, reactive oxygen species - known as oxidants - are harmful to cells in all organisms and have been linked to ageing. But a study from Chalmers University of Technology, Sweden, has now shown that low levels of the oxidant hydrogen peroxide can stimulate an enzyme that helps ...


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