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Fat-blocking effect of nanofibers discovered

Tiny balls of nano-sized cellulose fibres added to food reduced fat absorption by up to half

10-Aug-2018

This discovery could aid in the global battle against obesity, as experiments done in a simulated gastrointestinal tract showed that nanocellulose fibres 100 times smaller than the width of a human hair could cut fat absorption by up to 48 per cent. In animal experiments, rats fed with heavy ...

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Large-scale and sustainable 3D printing with the most ubiquitous natural material

08-Jun-2018

Cellulose is one of the most abundant and broadly distributed organic compound and industrial by-product on Earth. Yet, despite decades of extensive research, the bottom-up use of cellulose to fabricate 3D objects is still plagued with problems that restrict its practical applications: ...

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Flowing cells in a wavy microchannel for effective size-based cell sorting

17-May-2018

Nearly half a century ago scientists have noticed an interesting phenomenon that small particles flowing through a long tube can stay at a specific position along the cross-section of a tube. This is known as inertial focusing. Later, along with the development of microfluidic technology in ...

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A greener and cheaper technique for biofuel production

Bacterium isolated from mushroom converts plant material directly to butanol

10-Apr-2018

A team of engineers from the National University of Singapore (NUS) recently discovered that a naturally occurring bacterium, Thermoanaerobacterium thermosaccharolyticum TG57, isolated from waste generated after harvesting mushrooms, is capable of directly converting cellulose, a plant-based ...

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Unpacking asymmetric cell division

01-Mar-2018

Stem cells are the basic material from which mature, specialised cells such as muscle and blood cells are produced -- this process is known as differentiation. One way that stem cells do this without depleting themselves is through asymmetric cell division. Through asymmetric division, a stem ...

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Scaling to new heights with gecko-inspired adhesive

12-Jan-2018

Some animals, such as geckos, can easily climb up walls and across ceilings. But currently, no material exists that allows everyday people to scale walls or transverse ceilings as effortlessly. Now, scientists report a dry adhesive that could someday make it easier to defy gravity. Geckos can ...

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Singapore’s IP Office to Grant Merck’s Patent Application for CRISPR Technology

21-Dec-2017

Merck announced that the Intellectual Property Office of Singapore has issued a “Notice of Eligibility for Grant” for Merck’s patent application covering the company’s CRISPR technology used in a genomic-integration method for eukaryotic cells. "Singapore’s notice of patent allowance for Merck’s ...

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Researchers fold a protein within a protein

15-Nov-2017

A team from the NUS Yong Loo Lin School of Medicine (NUS Medicine) has invented a fundamentally new way of folding and protecting recombinant proteins. Sourced from the rapidly expanding field of synthetic biology, this protein-in-a-protein technology can improve functional protein yields by ...

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Herbal remedies containing aristolochic acid may cause liver cancer

20-Oct-2017

Scientists from Singapore and Taiwan have revealed a decisive link between Aristolochic Acids (AA), a natural product of some plants used in herbal remedies, and liver cancers. Using mutational signature analysis, the researchers found that liver tumours had been exposed to AA, which had mutated ...

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Eating meat linked to higher risk of diabetes

07-Sep-2017

While a plant-based diet is generally considered healthier than a meat-based diet in preventing the risk of diabetes, not all meats affect the risk equally. As Professor Koh Woon Puay, Professor of Clinical Sciences at Duke-NUS Medical School (Duke-NUS), and her team found out, higher intake of ...

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